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LICORICE ROOT EXTRACT

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Name

LICORICE ROOT EXTRACT

EINECS 283-895-2
CAS No. 8008-94-4 Density N/A
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula N/A Boiling Point N/A
Molecular Weight 0 Flash Point N/A
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 8008-94-4 (LICORICE EXTRACT) Hazard Symbols N/A
Synonyms

LIQUORICE EXTRACT;LICORICE ROOT;LICORICE ROOT EXTRACT;LICORICE ROOT FLUID EXTRACT;LICORICE ROOT POWDER;GLYCYRRHIZA GLABRA POWDER;GLYCYRRHIZA GLABRA ROOT POWDER;FEMA 2628

 

LICORICE ROOT EXTRACT Chemical Properties

Product Name: Licorice extract (CAS NO.8008-94-4)
Mol File: 8008-94-4.mol

LICORICE ROOT EXTRACT Uses

GB 2760-96: allowing the use of edible spices. Sweeteners; flavoring agent; surfactant.

LICORICE ROOT EXTRACT Production

Legumes take licorice (GlycyrRhiza uralensis), Glycyrrhiza inflata (G. Inflata) or foreign liquorice (G. Glabra) dry root and rhizome to remove fibrous root dry raw materials. With less than 60 ℃: warm water immersion, cut into 0.5cm slices below, plus 8 times the amount of water, boil countercurrent extraction cycle 8 times, the leaching solution set of natural sedimentation sedimentation tank 3h, the supernatant concentrated to thick paste , so that glycyrrhizic acid content is not less than 20% of the degrees, is a licorice extract. Amount of licorice extract obtained by adding water, constantly stirring and heating to make it melt, filter, in the filtrate slowly adding 85% ethanol to the solution of ethanol content of 65% or so, put it aside overnight, the supernatant, the remaining precipitation coupled with 65% ethanol, stirring, overnight, the supernatant, plus 65% ethanol extract of a merger three extract filtration, recovery of ethanol, water and ethanol to more than 7.0% glycyrrhizin content, ethanol content of 20% to 25%, with Ph value of ammonia solution adjusted to 7.5 ~ 8.5, put it aside, to clarify the supernatant filter formed.

LICORICE ROOT EXTRACT Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 209gm/kg/2Y-I (209000mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
Italian Journal of Neurological Sciences. Vol. 4, Pg. 493, 1983.
mouse LD50 intraperitoneal 1500mg/kg (1500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BLOOD: CHANGES IN SPLEEN
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
mouse LD50 oral > 7500mg/kg (7500mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
mouse LD50 subcutaneous 4gm/kg (4000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BLOOD: CHANGES IN SPLEEN
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
rat LD50 intraperitoneal 1420mg/kg (1420mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
rat LD50 oral 14200mg/kg (14200mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
rat LD50 subcutaneous 4200mg/kg (4200mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.

LICORICE ROOT EXTRACT Safety Profile

Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

LICORICE ROOT EXTRACT Specification

 Licorice extract ,its CAS NO. is 8008-94-4,the synonyms is Licorice root ; Licorice root extract ; Licorice root fluid extract ; Licorice root powder ; Glycyrrhiza glabra powder ; Glycyrrhiza glabra root powder ; Fema 2628 .

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