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Leucinocaine

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Name

Leucinocaine

EINECS 205-191-6
CAS No. 135-44-4 Density g/cm3
PSA 118.31000 LogP 4.34810
Solubility N/A Melting Point 171°
Formula C17H28N2O2•CH4O3S Boiling Point 417.1°Cat760mmHg
Molecular Weight 388.58 Flash Point 206°C
Transport Information N/A Appearance N/A
Safety Poison by subcutaneous, intravenous, and intraspinal routes. Used as a topical and infiltration anesthetic. When heated to decomposition it emits very toxic fumes of SOx and NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 135-44-4 (2-(diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate) Hazard Symbols N/A
Synonyms

p-Aminobenzoic acid-N-1-diethylamino-1-isobutylethanol methanesulfonate;S.P. 147;1-Pentanol, 2-(diethylamino)-4-methyl-, p-aminobenzoate (ester), monomethanesulfonate;N,N-Diethylleucinon-p-aminobenzoic acid methanesulfonate;Leucinocaine mesylate;p-Aminobenzoic acid N,N-diethylleucinol ester methanesulfonate;(2-diethylamino-4-methyl-pentyl) 4-aminobenzoate; methanesulfonic acid;p-Aminobenzoic acid beta-diethylaminoisohexyl ester methanesulfonate;2-(Diethylamino)-4-methyl-1-pentanol, p-aminobenzoate ester, methanesulfonate;Methanesulfonic acid, compd. with 2-(diethylamino)-4-methylpentyl P-aminobenzoate (1:1);1-Pentanol,2-(diethylamino)-4-methyl-,4- aminobenzoate (ester),monomethanesulfonate (salt);2-(Diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate;2-Methyl-4-diethylaminopentan-5-ol p-aminobenzoate;Panthesin;Panthesine;p-AMINOBENZOIC ACID-N,N-DIETHYLLEUCINOL ESTER METHANESULFONATE;METHANESULFONIC ACID, COMPOUND with 2-(DIETHYLAMINO)-4-METHYLPENTYL PAMINOBENZOATE (1:1);p-AMINOBENZOIC ACID-β-DIETHYLAMINOISOHEXYL ESTER METHANESULFONATE;

 

Leucinocaine Chemical Properties

IUPAC Name: [2-(Diethylamino)-4-methylpentyl] 4-aminobenzoate; methanesulfonic acid
Molecular Formula: C17H28N2O2•CH4O3S
Molecular Weight: 388.58g/mol
Freely Rotating Bonds: 10
Polar Surface Area: 32.78 Å2
Flash Point: 206 °C
Enthalpy of Vaporization: 67.04 kJ/mol
Boiling Point: 417.1 °C at 760 mmHg
Vapour Pressure: 3.65E-07 mmHg at 25°C
 The Cas Register Number of Leucinocaine is 135-44-4 .The chemical synonyms of Leucinocaine (CAS No.135-44-4) are 2-(Diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate ; Leucinocaine ; 2-Diethylamino-4-methyl-1-pentanol 4-aminobenoate monomethanesulfonate ; Leucinocaine mesylate ; Leucinocaine methanesulfonate ; Panthesin ; Panthesine .The molecular structure of  Leucinocaine (CAS No.135-44-4) is.

Leucinocaine Toxicity Data With Reference

1.    

scu-gpg LDLo:250 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 144 (1929),197.
2.    

scu-rbt LDLo:160 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 144 (1929),197.
3.    

ivn-rbt LDLo:20 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 144 (1929),197.
4.    

ivn-gpg LDLo:140 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 144 (1929),197.
5.    

ivn-gpg LDLo:20 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 144 (1929),197.

Leucinocaine Safety Profile

Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.

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