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N-Acetyl carnosine
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Name

N-Acetyl carnosine

 EINECS 260-123-2
CAS No. 56353-15-2 Density 1.343 g/cm3
PSA 124.18000 LogP -0.17040
Solubility Melting Point 253 - 260 C
Formula C11H16 N4 O4 Boiling Point 775.9 °C at 760 mmHg
Molecular Weight 268.272 Flash Point 423 °C
Transport Information OTH Appearance white to off-white powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 56353-15-2 (N-Acetyl carnosine) Hazard Symbols UN NO.
Synonyms

Histidine,N-(N-acetyl-b-alanyl)-,L- (6CI); L-Histidine, N-(N-acetyl-b-alanyl)-; Can-C; N-(N-Acetyl-b-alanyl)histidine; N-Acetyl-L-carnosine; N-Acetylcarnosine

 

N-Acetyl carnosine Synthetic route

3025-95-4

N-acetyl-β-alanine

71-00-1

L-histidine

56353-15-2

N-acetyl-β-alanyl-L-histidine

Conditions
ConditionsYield
With 2-chloro-1,3-dimethylimidazolinium chloride In ethanol at 40℃; for 3h; Concentration; Reagent/catalyst; Solvent; Temperature;97.9%

N-acetyl-β-alanyl chloride

O-(Trimethylsilyl)histidine

56353-15-2

N-acetyl-β-alanyl-L-histidine

Conditions
ConditionsYield
Stage #1: N-acetyl-β-alanyl chloride; O-(Trimethylsilyl)histidine In chloroform at -1 - 10℃; for 3h;
Stage #2: With water In chloroform at 30℃; for 2h; Temperature; Reagent/catalyst;		91.8 g
3025-95-4

N-acetyl-β-alanine

56353-15-2

N-acetyl-β-alanyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: thionyl chloride / chloroform / 3 h / 60 °C
2.1: chloroform / 3 h / -1 - 10 °C
2.2: 2 h / 30 °C
View Scheme
71-00-1

L-histidine

56353-15-2

N-acetyl-β-alanyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfuric acid / 3 h / Reflux
2.1: chloroform / 3 h / -1 - 10 °C
2.2: 2 h / 30 °C
View Scheme
1178531-12-8

(S)-((3R,3aR,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl) 5,6-bis(nitrooxy)hexanoate

56353-15-2

N-acetyl-β-alanyl-L-histidine

(S)-((3R,3aR,6R,6aR)-6-((S)-2-(3-acetamidopropanamido)-3-(1H-imidazol-4-yl)propanoyloxy)hexahydrofuro[3,2-b]furan-3-yl) 5,6-bis(nitrooxy)hexanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 90h;20%

N-Acetyl carnosine Chemical Properties

IUPAC Name: 2-(3-Acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid
Synonyms: (S)-2-(3-Acetylamino-propionylamino)-3-(3H-imidazol-4-yl)-propionic acid ; N-(N-acetyl-beta-alanyl)-L-histidine ; N-Aceyl-L-Carnosine
Product Categories: Protected amino acid & peptides ;Amino Acids & Derivatives
Molecular Structure of N-Acetyl-l-carnosine (CAS NO.56353-15-2) :
Molecular Formula of N-Acetyl-l-carnosine (CAS NO.56353-15-2) : C11H16N4O4
Molecular Weight of N-Acetyl-l-carnosine (CAS NO.56353-15-2) : 268.27
CAS NO: 56353-15-2
EINECS 260-123-2
Mol File: 56353-15-2.mol
Index of Refraction: 1.563
Surface Tension: 62.5 dyne/cm
Density: 1.343 g/cm3
Flash Point: 423 °C
Enthalpy of Vaporization: 118.45 kJ/mol
Boiling Point: 775.9 °C at 760 mmHg
Vapour Pressure: 2.47E-25 mmHg at 25°C
Melting point: 209-210°C
Appearance:White Crystalline Solid

N-Acetyl carnosine Uses

1. N-Acetyl-l-carnosine (CAS NO.56353-15-2) is used in the treatment of cataracts and in the treatment of UV-induced immunosuppression.
2. It is mainly for cell anti-oxidation, maintain pH balance of body, extend the cell life span.

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