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N-Ethylformamide

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Name

N-Ethylformamide

EINECS N/A
CAS No. 627-45-2 Density 0.950 g/mL at 20 °C(lit.)
PSA 29.10000 LogP 0.77910
Solubility N/A Melting Point -60.43°C (estimate)
Formula C3H7 N O Boiling Point 202-204 °C
Molecular Weight 73.0947 Flash Point 67°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by intraperitoneal and possibly other routes. When heated to decomposition it emits toxic vapors of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 627-45-2 (N-ETHYLFORMAMIDE) Hazard Symbols N/A
Synonyms

Ethylformamide;N-Ethylformamide; N-Formylethylamine; NSC 404522

Article Data 34

N-Ethylformamide Synthetic route

75-04-7

ethylamine

109-94-4

formic acid ethyl ester

627-45-2

N-formylethylamine

Conditions
ConditionsYield
for 2h; Ambient temperature;96%
Heating;
64-18-6

formic acid

79-24-3

Nitroethane

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With gold nano particles supported on rutile TiO2 In toluene at 70℃; under 750.075 Torr; for 8h; Inert atmosphere; chemoselective reaction;96%
64-18-6

formic acid

75-04-7

ethylamine

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With nano-sulfated titania In neat liquid at 20℃; for 0.5h; Green chemistry;90%
With silica gel for 0.0263889h; microwave irradiation;70%
for 0.5h; Heating;
75-04-7

ethylamine

122-51-0

orthoformic acid triethyl ester

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With dioxo[bis(sulfato-κO)]molybdenum In ethanol for 3.33333h; Reflux; Green chemistry;78%
624-79-3

ethyl isocyanide

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With acetic acid
1493-02-3

formyl fluoride

75-04-7

ethylamine

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With diethyl ether
107-31-3

Methyl formate

75-04-7

ethylamine

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With water
at 45 - 145℃;
75-04-7

ethylamine

75-87-6

chloral

A

67-66-3

chloroform

B

627-45-2

N-formylethylamine

Conditions
ConditionsYield
Destillation;
durch Destillation;
75-05-8

acetonitrile

627-45-2

N-formylethylamine

Conditions
ConditionsYield
With nickel at 125 - 145℃; under 100 - 36775.4 Torr; Hydrogenation;
624-79-3

ethyl isocyanide

64-19-7

acetic acid

A

627-45-2

N-formylethylamine

B

108-24-7

acetic anhydride

N-Ethylformamide Chemical Properties

Chemistry informtion about N-Ethylformamide (CAS NO.627-45-2) is:
IUPAC Name: N-Ethylformamide
Synonyms: Ethylformamide ; Formamide, N-Ethyl- ; N-Aethylformamid ; N-Ethyl-Formamid ; N-Formylethylamine ; N-Ethylformamide ; N-Formylethylamine 98+% ; Monoethylformamide
MF: C3H7NO
MW: 73.09
EINECS: 211-001-2 
Density: 0.868 g/cm3
Flash Point: 86.3 °C
Boiling Point: 185.7 °C at 760 mmHg
Vapour Pressure: 0.689 mmHg at 25°C 
Enthalpy of Vaporization: 42.19 kJ/mol
Refractive Index: n20/D 1.432
Following is the molecular structure of N-Ethylformamide (CAS NO.627-45-2) is:

N-Ethylformamide Toxicity Data With Reference

Safty information about N-Ethylformamide (CAS NO.627-45-2) is:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intraperitoneal > 1200mg/kg (1200mg/kg)   Therapie. Vol. 27, Pg. 873, 1972.
rat LD50 unreported 3gm/kg (3000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 645, 1968.

N-Ethylformamide Consensus Reports

Reported in EPA TSCA Inventory.

N-Ethylformamide Safety Profile

Moderately toxic by intraperitoneal and possibly other routes. When heated to decomposition it emits toxic vapors of NOx
Safety Statements:
S23:Do not breathe vapour. 
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: LQ2725000

N-Ethylformamide Specification

To protect yourself, you can put on eyeshields and gloves.

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