Product Name: n-Nitrosodimethylamine (62-75-9)

Molecular Formula: C₂H₆N₂O
Molecular Weight: 74.08g/mol
Mol File: 62-75-9.mol
Einecs: 200-549-8
Appearance: yellow oily liquid
Melting Point: 50°C
Boiling point: 153 °C 774 mm Hg(lit.)
Flash Point: 36.1 °C
Density: 1.01 g/mL(lit.)
Vapor pressure: 5 mm Hg ( 20 °C)
Refractive index: n20/D 1.437(lit.)
Water Solubility: soluble
Stability: Stability Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases, strong reducing agents.
Product Categories: Nitrosamine;NA - NIEPA ; TO-7: N-Nitrosodimethylamine By Capillary GC-MS ; AliphaticsVolatiles/ Semivolatiles ; Alpha Sort ; Amines ; Chemical Class ; EPA TO Methods ; N ; N-OAlphabetic
Synonyms of  n-Nitrosodimethylamine (62-75-9): (ch3)2nno ; 1,1-dimethyl-2-oxohydrazine ; dimethylamine, n-nitroso ; dimethylnitrosamin ; dimethylnitrosoamine ; dimethyl-nitroso-amine ; dmn ; dmna .

Organic synthesis intermediates. Used in rocket fuel, antioxidants and other manufacturing.

Be 245g dimethylamine hydrochloride and mixing hydrochloric acid heated to 70-75 ℃, adding 235g of sodium nitrite in 150ml water slurry liquid, while adding hydrochloric acid to make exactly acidic reactant. Canadian Bi, heating 2h, and then distilled to nearly dry, add water and then evaporated, the distillate combined with 300g of saturated potassium carbonate to make, take the upper vacuum fractionation, may close 200gN-nitroso-dimethylamine, the yield of nearly 90 %.

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 ,1972,p. 95.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 ,1972,p. 95.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. Community Right-To-Know List. EPA Extremely Hazardous Substances List.

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. A transplacental carcinogen. Human poison by ingestion. Experimental poison by ingestion, inhalation, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by ingestion: ulceration or bleeding from small intestine, nausea or vomiting, and fever. Experimental reproductive effects. Human mutation data reported. Has caused fatal liver disease in humans. When heated to decomposition it emits toxic fumes of NO_x. See also NITROSAMINES.
Analytical Methods: 
For occupational chemical analysis use OSHA: #27.
When heated to decomposition, n-Nitrosodimethylamine emits toxic fumes of nitrogen oxides. Avoid exposure to ultraviolet light.
Safety Information of  n-Nitrosodimethylamine (62-75-9):
Hazard Codes: T+,N,F
Risk Statements: 45-25-26-48/25-51/53-39/23/24/25-23/24/25-11 
11:  Highly Flammable 
23:  Toxic by inhalation 
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
26:  Very Toxic by inhalation 
39:  Danger of very serious irreversible effects
45:  May cause cancer 
48:  Danger of serious damage to health by prolonged exposure 
51:  Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 53-45-61-36/37
36:  Wear suitable protective clothing 
37:  Wear suitable gloves 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

OSHA PEL: Cancer Suspect Agent
ACGIH TLV: Animal Carcinogen
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

For occupational chemical analysis use OSHA: #27.

 n-Nitrosodimethylamine (62-75-9) is a yellow oily liquid with a faint characteristic odor. It can reasonably be expected to be a carcinogen. Used as an antioxidant, as an additive for lubricants and as a softener of copolymers. An intermediate in 1,1-dimethylhydrazine production.