Basic Information | Post buying leads | Suppliers |
Name |
N-Phenoxyisopropyl-n-benzyl-β-chloroethylamine |
EINECS | N/A |
CAS No. | 59-96-1 | Density | 1.102g/cm3 |
PSA | 12.47000 | LogP | 4.19490 |
Solubility | N/A | Melting Point |
38-40oC |
Formula | C18H22 Cl N O | Boiling Point | 381.5°Cat760mmHg |
Molecular Weight | 303.832 | Flash Point | 184.5°C |
Transport Information | N/A | Appearance | N/A |
Safety | Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intravenous and intracerebral routes. Moderately toxic by ingestion. Human reproductive effects by ingestion: spermatogenesis. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
Benzylamine,N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)- (8CI); (?à)-Phenoxybenzamine; 688A;Bensylyt; Benzylyt; Dibenylin; Dibenyline; Dibenzyline;N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine;N-Phenoxyisopropyl-N-benzyl-b-chloroethylamine; Phenoxybenzamine |
IUPAC Name: N-Benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine
Synonyms of N-Phenoxyisopropyl-n-benzyl-β-chloroethylamine (CAS NO.14026-03-0) : (±)-Phenoxybenzamine ; Bensylyte ; Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)- ; N-(2-chloroethyl)-N-(phenylmethyl)-1-(phenyloxy)propan-2-amine ; N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine ; N-Phenoxyisopropyl-N-benzyl-b-chloroethylamine
CAS NO:14026-03-0
Molecular Formula:C18H22ClNO
Molecular Weight :303.8264
Molecular Structure :
Index of Refraction:1.559
Surface Tension: 40.7 dyne/cm
Density: 1.102 g/cm3
Flash Point: 184.5 °C
Enthalpy of Vaporization: 62.97 kJ/mol
Boiling Point: 381.5 °C at 760 mmHg
Vapour Pressure: 5.07E-06 mmHg at 25°C
N-Phenoxyisopropyl-n-benzyl-β-chloroethylamine (CAS NO.14026-03-0) is is used as intermediate in organic synthesis.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 10mg/kg (10mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 195, 1973. | |
guinea pig | LD50 | oral | 500mg/kg (500mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 195, 1973. | |
mouse | LD50 | oral | 1535mg/kg (1535mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 195, 1973. | |
rat | LD50 | intracrebral | 3400ug/kg (3.4mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archivum Immunologiae et Therapiae Experimentalis. Vol. 24, Pg. 223, 1976. |
rat | LD50 | oral | 2500mg/kg (2500mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 195, 1973. |
IARC Cancer Review: Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 ,1980,p. 185.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 ,1975,p. 223.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intravenous and intracerebral routes. Moderately toxic by ingestion. Human reproductive effects by ingestion: spermatogenesis. Experimental reproductive effects. When N-Phenoxyisopropyl-n-benzyl-β-chloroethylamine (CAS NO.14026-03-0) is heated to decomposition it emits very toxic fumes of Cl− and NOx.