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N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

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Name

N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

EINECS 1592732-453-0
CAS No. 64987-85-5 Density 1.42 g/cm3
PSA 101.06000 LogP 0.20080
Solubility chloroform: 50 mg/mL,DMF: soluble Melting Point 180-182 °C(lit.)
Formula C16H18N2O6 Boiling Point 501.7 °C at 760 mmHg
Molecular Weight 334.329 Flash Point 257.2 °C
Transport Information N/A Appearance white crystalline solid
Safety 26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 64987-85-5 (N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate) Hazard Symbols IrritantXi
Synonyms

1H-Pyrrole-2,5-dione,1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]- (9CI);4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester;NSC 344483;SMCC;Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate;

Article Data 3

N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Specification

The cas register number of N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate is 64987-85-5. It also can be called as  4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester and the IUPAC Name about this chemical is (2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate. It belongs to the following product categories, such as Maleimide Derivatives, Cross Linking Reagents, MTS & Sulfhydryl Active Reagents and so on. This chemical can be used in the preparation of rabbit Fab'-peroxidase conjugates.

Physical properties about N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate are: (1)ACD/LogP: -0.39; (2)ACD/LogD (pH 5.5): -0.39; (3)ACD/LogD (pH 7.4): -0.39; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 14.65; (7)ACD/KOC (pH 7.4): 14.65; (8)#H bond acceptors: 8; (9)#Freely Rotating Bonds: 5; (10)Polar Surface Area: 101.06Å2; (11)Index of Refraction: 1.598; (12)Molar Refractivity: 79.95 cm3; (13)Molar Volume: 234.3 cm3; (14)Polarizability: 31.69x10-24cm3; (15)Surface Tension: 64.7 dyne/cm; (16)Enthalpy of Vaporization: 77.06 kJ/mol; (17)Vapour Pressure: 3.38E-10 mmHg at 25°C.

Uses of N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: it can be used to produce dimyristoyl-N-{[4-(maleimidomethyl)cyclohexyl]carbonyl}phosphatidylethanolamine with Dimyristoyl-glycerin-a-kephalin at Ambient temperature. This reaction will need reagent triethylamine and solvent CHCl3 with reaction time of 24 hours. The yield is about 52%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C3N(OC(=O)C2CCC(CN1C(=O)\C=C/C1=O)CC2)C(=O)CC3
(2)InChI: InChI=1/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
(3)InChIKey: JJAHTWIKCUJRDK-UHFFFAOYAC
(4)Std. InChI: InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
(5)Std. InChIKey: JJAHTWIKCUJRDK-UHFFFAOYSA-N

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