Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Norandrostenedione

Related Products

Hot Products

Name

Norandrostenedione

EINECS 211-995-8
CAS No. 734-32-7 Density 1.13 g/cm3
PSA 34.14000 LogP 3.69730
Solubility 191mg/L at 20℃ Melting Point ?72°C(lit.)
Formula C18H24O2 Boiling Point 433.4 °C at 760 mmHg
Molecular Weight 272.387 Flash Point 161.8 °C
Transport Information N/A Appearance N/A
Safety 16-26-36/37/39-45 Risk Codes 11-34
Molecular Structure Molecular Structure of 734-32-7 (Norandrostenedione) Hazard Symbols FlammableF, CorrosiveC
Synonyms

(+)-19-Norandrost-4-en-3,17-dione;(+)-19-Norandrost-4-ene-3,17-dione;(+)-Estr-4-ene-3,17-dione;19-Nor-4-androstenedione;19-Norandrost-4-ene-3,17-dione;3,17-Dioxo-19-norandrost-4-ene;NSC 12164;Nordione;d-19-Norandrost-4-ene-3,17-dione;

Article Data 58

Norandrostenedione Synthetic route

434-22-0

19-nortestosterone

734-32-7

estra-4-ene-3,17-dione

Conditions
ConditionsYield
In acetic acid for 1h; Ambient temperature;96%
With tert.-butylhydroperoxide; 3 A molecular sieve; zircornium(IV) n-propoxide In dichloromethane for 17h;96%
With zirconium(IV) tert-butoxide; chloral In dichloromethane at 20℃; for 8h;73%

Norandrostenedione Specification

The IUPAC name of Estr-4-ene-3,17-dione is (8R,9S,10R,13S,14S)-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione . With the CAS registry number 734-32-7, it is also named as 19-Norandrostenedione ; NSC 12164 ; delta4-Estrene-3,17-dione . The product's categories are steroids, miscellaneous biochemicals, intermediates & fine chemicals and pharmaceuticals.

The Estr-4-ene-3,17-dione is used as Norethindrone intermediate. It was available without prescription in United States until 2005. It was marketed as a prohormone in United States, but it is now classified as a Schedule III drug. Estr-4-ene-3,17-dione is readily metabolized to nandrolone after oral administration, but its potency to transactivate the androgen receptor dependent reporter gene expression is 10 times lower as compared to dihydrotestosterone (DHT).

This product is highly flammable. It can cause burns. Keep away from sources of ignition. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.42 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 2.42 ; (4)ACD/LogD (pH 7.4): 2.42 ; (5)ACD/BCF (pH 5.5): 40.49 ; (6)ACD/BCF (pH 7.4): 40.49 ; (7)ACD/KOC (pH 5.5): 492.24 ; (8)ACD/KOC (pH 7.4): 492.24 ; (9)#H bond acceptors: 2 ; (10)Index of Refraction: 1.555 ; (11)Molar Refractivity: 77.05 cm3 ; (12)Molar Volume: 239.8 cm3 ; (13)Polarizability: 30.54×10-24 cm3 ; (14)Surface Tension: 43.3 dyne/cm ; (15)Enthalpy of Vaporization: 68.94 kJ/mol ; (16)Vapour Pressure: 1.03E-07 mmHg at 25°C ; (17)Tautomer Count: 16 ; (18)Exact Mass: 272.17763 ; (19)MonoIsotopic Mass: 272.17763 ; (20)Topological Polar Surface Area: 34.1 ; (21)Heavy Atom Count: 20.

People can use the following data to convert to the molecule structure. SMILES: O=C4/C=C3/CC[C@@H]2[C@H](CC[C@@]1(C(=O)CC[C@H]12)C)[C@H]3CC4; InChI: InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1.

The Estr-4-ene-3,17-dione has many suppliers, such as Emerald-Shanghai Incorporation, Techwin Bio.& Pharm.Technology Limited, Xianju Green Leaf Pharmaceutical Factory and Yangzhou Lianhuan Pharmaceutical Co., Ltd..

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 734-32-7