Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Oxyclozanide

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Oxyclozanide

EINECS 218-904-0
CAS No. 2277-92-1 Density 1.784 g/cm3
PSA 69.56000 LogP 5.69010
Solubility 29mg/L(25 oC) Melting Point 77-81 °C
Formula C13H6Cl5NO3 Boiling Point 446 °C at 760 mmHg
Molecular Weight 401.461 Flash Point 223.5 °C
Transport Information UN 3077 Appearance white to yellowish powder
Safety 60-61-36-26 Risk Codes 22-50/53-36/37/38
Molecular Structure Molecular Structure of 2277-92-1 (Oxyclozanide) Hazard Symbols HarmfulXn,DangerousN,IrritantXi
Synonyms

Salicylanilide,3,3',5,5',6-pentachloro-2'-hydroxy- (7CI,8CI);3,3',5,5',6-Pentachloro-2,2'-dihydroxybenzanilide;3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilide;3,5,6,3',5'-Pentachloro-2,2'-dihydroxybenzanilide;Diplin;ICI 46638;Oxyclozanid;Zanil;Zanilox;

 

Oxyclozanide Synthetic route

2277-92-1

oxyclozanide

71-43-2

benzene

oxyclozanidebenzene hemisolvate

Conditions
ConditionsYield
at 20℃; for 168h;
106-42-3

para-xylene

2277-92-1

oxyclozanide

oxyclozanide xylene hemisolvate

Conditions
ConditionsYield
at 20℃; for 168h;
2277-92-1

oxyclozanide

108-88-3

toluene

oxyclozanide toluene hemisolvate

Conditions
ConditionsYield
at 20℃; for 168h;
2277-92-1

oxyclozanide

108-90-7

chlorobenzene

oxyclozanide chlorobenzene hemisolvate

Conditions
ConditionsYield
at 20℃; for 168h;

Oxyclozanide Specification

The Oxyclozanide is an organic compound with the formula C13H6Cl5NO3. The IUPAC name of this chemical is 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide. With the CAS registry number 2277-92-1, it is also named as 2,2'-Dihydroxy-3,3',5,5',6-pentachlorobenzanilide. The product's classification codes are Anthelmintics; Anti-Infective Agents; Antiparasitic Agents; Antiplatyhelmintic agents; Drug / Therapeutic Agent. Besides, it should be stored at temperature of 0 - 6 °C. It is a salicylanilide anthelmintic. It is used in the treatment and control of Fascioliasis in ruminants mainly domestic animals like Cattle, Sheep and Goats.

Physical properties about Oxyclozanide are: (1)ACD/LogP: 8.67; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 8.16; (4)ACD/LogD (pH 7.4): 6.19; (5)ACD/BCF (pH 5.5): 706340; (6)ACD/BCF (pH 7.4): 7634.49; (7)ACD/KOC (pH 5.5): 382470.31; (8)ACD/KOC (pH 7.4): 4133.94; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 38.77 Å2; (13)Index of Refraction: 1.722; (14)Molar Refractivity: 89.06 cm3; (15)Molar Volume: 224.9 cm3; (16)Polarizability: 35.3×10-24cm3; (17)Surface Tension: 72.4 dyne/cm; (18)Density: 1.784 g/cm3; (19)Flash Point: 223.5 °C; (20)Enthalpy of Vaporization: 73.12 kJ/mol; (21)Boiling Point: 446 °C at 760 mmHg; (22)Vapour Pressure: 1.43E-08 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed and very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. This material and its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc2c(C(=O)Nc1cc(Cl)cc(Cl)c1O)c(O)c(Cl)cc2Cl
(2)InChI: InChI=1/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
(3)InChIKey: JYWIYHUXVMAGLG-UHFFFAOYAW
(4)Std. InChI: InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
(5)Std. InChIKey: JYWIYHUXVMAGLG-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LDLo oral 60mg/kg (60mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Veterinary Record. Vol. 78, Pg. 267, 1966.
domestic animals - goat/sheep LDLo intravenous 10mg/kg (10mg/kg)   Veterinary Record. Vol. 78, Pg. 267, 1966.
domestic animals - goat/sheep LDLo oral 60mg/kg (60mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Veterinary Record. Vol. 78, Pg. 267, 1966.
rat LD50 oral 1gm/kg (1000mg/kg)   Nature. Vol. 210, Pg. 744, 1966.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2277-92-1