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Cas Database |
| Name |
PF 00299804-03; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-Butenamide |
EINECS | N/A |
| CAS No. | 1110813-31-4 | Density | 1.344 |
| PSA | 79.38000 | LogP | 5.23900 |
| Solubility | DMSO, Methanol (Sparingly) | Melting Point |
>187°C (dec.) |
| Formula | C24H25ClFN5O2 | Boiling Point | 665.7±55.0 °C(Predicted) |
| Molecular Weight | 469.94 | Flash Point | N/A |
| Transport Information | N/A | Appearance | White to Off-White Solid |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
PF299804; pf-00299804-03; (2e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-2-butenamide; (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-Methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide; pf-299 |
Article Data | 9 |
PF 00299804-03; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-Butenamide Specification
Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.
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Dacomitinib (PF299804)
