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Name	PRIMAQUINE	EINECS	201-987-2
CAS No.	90-34-6	Density	1.0313 (rough estimate)
PSA	60.17000	LogP	3.55600
Solubility	718.4g/L(25 oC)	Melting Point	25°C
Formula	C15H21 N3 O	Boiling Point	bp0.2 175-179°
Molecular Weight	259.351	Flash Point	N/A
Transport Information	N/A	Appearance	N/A
Safety	Poison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Quinoline,8-[(4-amino-1-methylbutyl)amino]-6-methoxy- (6CI,8CI); (?à)-Primaquine;6-Methoxy-8-[4-amino-1-methylbutylamino]quinoline;8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline; NSC 27296; Neo-Quipenyl;Primachin; Primaquin; Primaquine; SN 13272; WR 2975; dl-Primaquine	Article Data	17

PRIMAQUINE Chemical Properties

IUPAC Name: 4-N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine
Synonyms: 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline ; N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine
Molecular Structure:
Molecular Formula: C₁₅H₂₁N₃O
Molecular Weight : 259.35
CAS NO: 90-34-6
EINECS: 201-987-2
Index of Refraction: 1.616
Surface Tension: 48 dyne/cm
Density: 1.126 g/cm³
Flash Point: 226.6 °C
Enthalpy of Vaporization: 71.01 kJ/mol
Boiling Point: 451.1 °C at 760 mmHg
Vapour Pressure: 2.5E-08 mmHg at 25°C
Appearance: Primaquine (CAS NO.90-34-6) is viscous liquid.
Solubility: Primaquine (CAS NO.90-34-6) is soluble in ether.

PRIMAQUINE Uses

Primaquine (CAS NO.90-34-6) is effective drugs for teatment with vivax malaria and block all types of malaria transmission .

PRIMAQUINE Toxicity Data With Reference

1.	sce-rat-orl 8 mg/kg	SYXUD2 Shandong Yixueyuan Xuebao. Journal of Shandong Medical College 23 (1985),26.
2.	orl-mus LD50:100 mg/kg	AMACCQ Antimicrobial Agents and Chemotherapy. 12 (1977),51.
3.	ivn-mus LD50:15,900 µg/kg	ANTCAO Antibiotics and Chemotherapy. 12 (1962),103.

PRIMAQUINE Safety Profile

Poison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

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