Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Name	Papaverine hydrochloride	EINECS	200-502-1
CAS No.	61-25-6	Density	N/A
PSA	49.81000	LogP	4.66200
Solubility	freely soluble in water	Melting Point	226 °C (dec.)
Formula	C₂₀H₂₁NO₄^.HCl	Boiling Point	483.2 °C at 760 mmHg
Molecular Weight	375.852	Flash Point	172.2 °C
Transport Information	N/A	Appearance	Crystalline solid
Safety	22	Risk Codes	22
Molecular Structure		Hazard Symbols	Xn
Synonyms	Vasal;Vasorin;Spasmo Nit;Therapav;Paveron;Ro-Papav;Pavadel;Pavagen;Pavakey;Pavased;Vasospan;1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride;6,7,3',4'-Tetramethoxy-1-benzylisoquinoline hydrochloride;6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)isoquinoline hydrochloride;Isoquinoline,1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-, hydrochloride (9CI);Isoquinoline, 6,7-dimethoxy-1-veratryl-, hydrochloride (8CI);6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride;Papaverine hydrochloride;Papaverinium chloride;Papaversan;Paptial TR;Pavabid;Pavacap;Pavacen;Artegodan;Cardiospan;Cardoverina;Cepaverin;Cerebid;Cerespan;Dispamil;Drapavel;Dynovas;Myobid;Optenyl;Pameion;Panergon;Papavarine chlorhydrate;	Article Data	7

Papaverine hydrochloride Chemical Properties

The Molecular Structure of Papaverine hydrochloride (CAS NO.61-25-6):

MF: C₂₀H₂₂ClNO₄
MW: 375.85
Melting point: 226 ºC
Water Solubility: freely soluble
Stability: Stable, but may be light sensitive
Appearance: Crystalline Solid
Product Categories: Quinoline&Isoquinoline;Alkaloids;Biochemistry;Isoquinoline Alkaloids;Intermediates & Fine Chemicals;Pharmaceuticals
InChI
InChI=1/C20H21NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-8,10-12H,9H2,1-4H3;1H
Smiles
Cl.c12c(cc(OC)c(c2)OC)ccnc1Cc1cc(c(OC)cc1)OC
IUPAC Name: 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline

Papaverine hydrochloride Uses

Papaverine hydrochloride (CAS NO.61-25-6) can be uese as Smooth muscle relaxant that found in opium. Vasodilator (cerebral).

Papaverine hydrochloride Toxicity Data With Reference

1.	cyt-ham:fbr 125 mg/L	ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the National Hygiene Sciences. 96 (1978),55.
2.	cyt-ham:lng 340 mg/L	GMCRDC Gann Monograph on Cancer Research. 27 (1981),95.
3.	orl-wmn TDLo:300 mg/kg:CVS	CTOXAO Clinical Toxicology. 18 (1981),417.
4.	orl-rat LD50:360 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),200.
5.	ipr-rat LD50:64 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 6 (1956),454.
6.	scu-rat LD50:368 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 6 (1956),454.
7.	ivn-rat LD50:20 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 123 (1960),264.
8.	idu-rat LD50:71 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155.
9.	orl-mus LD50:130 mg/kg	JOETD7 Journal of Ethnopharmacology. 6 (1982),127.
10.	ipr-mus LD50:108 mg/kg	JMCMAR Journal of Medicinal Chemistry. 16 (1973),1063.
11.

Papaverine hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Papaverine hydrochloride Safety Profile

Poison by ingestion, intraperitoneal, intraduodenal, intravenous, and subcutaneous routes. Human systemic effects: metabolic acidosis, pulse rate increase. An experimental teratogen. Mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and HCl. See also PAPAVERINE.
Hazard Codes: Harmful Xn Corrosive CF
Risk Statements: 22-34-11
R22: Harmful if swallowed
R34: Causes burns
R11: Highly flammable
Safety Statements: 22-45-36/37/39-26-16
S22: Do not breathe dust
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S16: Keep away from sources of ignition
RIDADR: UN 1544 6.1/PG 3
WGK Germany: 1
RTECS: NW8575000
F: 8
HazardClass: 6.1
PackingGroup: III

Papaverine hydrochloride Specification

Papaverine hydrochloride (CAS NO.61-25-6) is also called as 6,7-Dimethoxy-1-veratrylisoquinoline hcl ; 6,7-Dimethoxy-1-veratryl-isoquinoline hydrochloride ; 6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)-isoquinoline hydrochloride ; 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride ; 1-[(3',4'-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline hcl ; Papaverine hcl ; Papaverine hydrochloride ; 1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxy-isoquinolinhydrochloride .