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Potassium hydrogen phthalate

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Name

Potassium hydrogen phthalate

EINECS 212-889-4
CAS No. 877-24-7 Density 1.006g/mLat 20°C
PSA 77.43000 LogP -0.25170
Solubility 80 g/L (20 °C) in water Melting Point 295-300 °C
Formula C8H6O4.K Boiling Point 378.3 °C at 760 mmHg
Molecular Weight 204.224 Flash Point 196.7 °C
Transport Information UN 1789 8/PG 3 Appearance White crystalline powder
Safety 26-36-24/25-22-45-36/37/39 Risk Codes 36/38-36/37/38-34
Molecular Structure Molecular Structure of 877-24-7 (Potassium hydrogen phthalate) Hazard Symbols IrritantXi,CorrosiveC
Synonyms

1,2-Benzenedicarboxylicacid, monopotassium salt (9Cl);Phthalic acid, monopotassium salt (8Cl);Hydrogen potassium phthalate;AI3-51765;Monopotassium 1,2-benzenedicarboxylate;Monopotassium phthalate;Potassium acid phthalate;Potassium biphthalate;

Article Data 4

Potassium hydrogen phthalate Synthetic route

C8H4(2)HO4(1-)*K(1+)

877-24-7

potassium hydrogen phthalate

Conditions
ConditionsYield
With water-d2 In water at 34.9℃; Equilibrium constant;
88-99-3

benzene-1,2-dicarboxylic acid

potassium hydroxide

877-24-7

potassium hydrogen phthalate

Conditions
ConditionsYield
In water mixed at 1:1 ratio, evapd.; recrystn.;
88-99-3

benzene-1,2-dicarboxylic acid

877-24-7

potassium hydrogen phthalate

Conditions
ConditionsYield
With potassium hydroxide In water
With potassium hydroxide In water at 20℃; for 0.5h;
4702-13-0

N-phthaloylglycine

877-24-7

potassium hydrogen phthalate

Conditions
ConditionsYield
With potassium hydroxide In ethanol at 20℃; for 4h;
85-44-9

phthalic anhydride

877-24-7

potassium hydrogen phthalate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 180 °C
2: potassium hydroxide / ethanol / 4 h / 20 °C
View Scheme
33100-27-5

15-crown-5

877-24-7

potassium hydrogen phthalate

C8H5O4(1-)*C12H24KO6

Conditions
ConditionsYield
In water at 20℃; for 12h;100%

hexammine cobalt(III) chloride

877-24-7

potassium hydrogen phthalate

hexaamminecobalt(III) chloride hydrogen phthalate trihydrate

Conditions
ConditionsYield
In water byproducts: KCl; dissolving of (Co(NH3)6)Cl3 (1 equiv.) in hot water, addn. of potassium hydrogen phthalate (3 equiv.); slow cooling; crystn. for a few hours; filtration, crystn. from supernatant soln., combining of cryst.; drying in air; elem. anal.;99%
877-24-7

potassium hydrogen phthalate

88-99-3

benzene-1,2-dicarboxylic acid

85-44-9

phthalic anhydride

Conditions
ConditionsYield
Stage #1: benzene-1,2-dicarboxylic acid With trichloroisocyanuric acid; triphenylphosphine In dichloromethane at 0 - 20℃;
Stage #2: potassium hydrogen phthalate In dichloromethane at 20℃; for 1h;
95%
877-24-7

potassium hydrogen phthalate

Methanesulfonic acid 2-[2-(2-prop-2-ynyloxy-ethoxy)-ethoxy]-ethyl ester

1408059-52-8

2-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With sodium iodide In N,N-dimethyl-formamide at 80℃;94%
With sodium iodide In N,N-dimethyl-formamide at 80℃;5.7 g
877-24-7

potassium hydrogen phthalate

6018-89-9

nickel(II) acetate tetrahydrate

822-36-6

4-Methylimidazole

[Ni(4-methylimidazole)2(phthalate)(H2O)]

Conditions
ConditionsYield
In ethanol; water aq. soln. of Ni salt was added to warm soln. of K salt and 4-methylimidazole in EtOH; stirred under reflux for 1 h; filtered; washed (H2O, EtOH); dried in air; elem. anal.;90%

Potassium hydrogen phthalate Specification

The Hydrogen potassium phthalate with CAS registry number of 877-24-7 is also known as 1,2-Benzenedicarboxylic acid, potassium salt (1:1). The IUPAC name is Potassium 2-carboxybenzoate. It belongs to product categories of Inorganic & Organic chemicals; Classes of Metal Compounds; K (Potassium) Compounds (excluding simple potassium salts); Typical Metal Compounds. Its EINECS registry number is 212-889-4. In addition, the formula is C8H6O4.K and the molecular weight is 204.22. This chemical is a white crystalline powder and shouold be sealed in cool ang dry place. What's more, it is used as analytical reagent and a buffering agent or sodium hydroxide.

Physical properties about Hydrogen potassium phthalate are: (1)ACD/LogP: 0.81; (2)ACD/LogD (pH 5.5): -1.98; (3)ACD/LogD (pH 7.4): -3.3; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 4; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 2; (11)Flash Point: 196.7 °C; (12)Enthalpy of Vaporization: 66.05 kJ/mol; (13)Boiling Point: 378.3 °C at 760 mmHg; (14)Vapour Pressure: 2.14E-06 mmHg at 25 °C.

Preparation of Hydrogen potassium phthalat. Firstly, potassium is dissolved in water and heated under stirring. Meanwhile, adding phthalic anhydride in multiple for 30 minutes. Secondly, the reaction solution is filtered, concentrated to saturation and cooled to room temperature. At last, product is obtained by crystallization and drying.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. Besides, It may cause burns. During using it, wear suitable protective clothing, gloves and eye/face protection. Avoid contact with skin, eyes and do not breathe dust. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice. In case of accident or if you feel unwell seek medical advice immediately.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)C(=O)[O-].[K+]
2. InChI: InChI=1S/C8H6O4.K/c9-7(10)5-3-1-2-4-6(5)8(11)12;/h1-4H,(H,9,10)(H,11,12);/q;+1/p-1
3. InChIKey: IWZKICVEHNUQTL-UHFFFAOYSA-M

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 skin > 1gm/kg (1000mg/kg)   Kodak Company Reports. Vol. 21MAY1971,
rat LD50 oral > 3200mg/kg (3200mg/kg)   Kodak Company Reports. Vol. 21MAY1971,

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