Vercirnon

There total 8 articles about Vercirnon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

Reference yield:

698394-72-8

4-tert-butyl-N-[4-chloro-2-(pyridine-4-carbonyl)-phenyl]-benzenesulfonamide

698394-73-9

N-{4-chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(1,1-dimethylethyl) benzenesulfonamide

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

Reference yield:

106-47-8

4-chloro-aniline

698394-73-9

N-{4-chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(1,1-dimethylethyl) benzenesulfonamide

Guidance literature:

Multi-step reaction with 3 steps

1.1: boron trichloride / Trichloroethylene; dichloromethane / 0.17 h / 0 °C

1.2: 14.5 h / 20 - 85 °C

1.3: 1.5 h / 20 - 115 °C

2.1: pyridine; dmap / 24 h / 60 - 75 °C

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16.5 h / 0 - 20 °C

With pyridine; dmap; boron trichloride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Trichloroethylene;

Reference yield:

52482-36-7

morpholin-4-yl(pyridin-4-yl)methanone

698394-73-9

N-{4-chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(1,1-dimethylethyl) benzenesulfonamide

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -30 - -20 °C / Inert atmosphere

1.2: 4 h / 15 - 25 °C / Inert atmosphere

1.3: 4 h / 55 - 65 °C

2.1: pyridine; dmap / 24 h / 60 - 75 °C

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16.5 h / 0 - 20 °C

With pyridine; dmap; n-butyllithium; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;