Etoricoxib impurity Q

Base Information

Chemical Name:Etoricoxib impurity Q
CAS No.:292067-97-1
Molecular Formula:C18H15ClN2S
Molecular Weight:326.849
Hs Code.:
Mol file:292067-97-1.mol

Synonyms:5-chloro-6'-methyl-3-[4-(methylthio)phenyl]-2,3'-bipyridine;5-chloro-3-(4-(methylthio)phenyl)-2-(2-methyl-5-pyridinyl)pyridine;5-chloro-3-(4-methylthiophenyl)-6'-methyl-[2,3']bipyridine;

Suppliers and Price of Etoricoxib impurity Q

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Etoricoxib impurity Q

Chemical Property:

PSA：51.08000
LogP:5.49430

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Etoricoxib impurity Q

There total 13 articles about Etoricoxib impurity Q which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: (2Z,4Z)-4-Chloro-5-dimethylamino-1-(6-methyl-pyridin-3-yl)-2-(4-methylsulfanyl-phenyl)-penta-2,4-dien-1-one

: 292067-97-1
5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Guidance literature:: With ammonium hydroxide; In water;
DOI:10.1002/anie.201906080

Reference yield: 74.0%

: vinamidinium hexafluorophosphate

: 221615-72-1
1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone

: 292067-97-1
5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine

Guidance literature:: 1-(6-methyl-3-pyridinyl)-2-[4-(methyl sulfide)phenyl]ethanone; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃;

vinamidinium hexafluorophosphate; With acetic acid; trifluoroacetic acid; at 20 ℃;

With ammonium hydroxide; for 6h; Heating;
DOI:10.1016/j.bmcl.2005.06.080