4-Chloro-1H-indol-7-amine

Base Information

Chemical Name:4-Chloro-1H-indol-7-amine
CAS No.:292636-12-5
Molecular Formula:C₈H₇ClN₂
Molecular Weight:166.61
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70477725
Wikidata:Q82310603
Mol file:292636-12-5.mol

Synonyms:4-Chloro-1H-indol-7-amine;292636-12-5;7-Amino-4-chloro indole;7-AMINO-4-CHLOROINDOLE;1H-Indol-7-amine, 4-chloro-;SCHEMBL15826681;AMY9957;DTXSID70477725;MFCD11007923;AKOS006303939;AS-77306;SY023623;CS-0044105;FT-0708571;I11397

Suppliers and Price of 4-Chloro-1H-indol-7-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-1H-indol-7-amine 95+%
1g
$ 451.00

Chemenu
4-chloro-1H-indol-7-amine 95%
1g
$ 426.00

American Custom Chemicals Corporation
7-AMINO-4-CHLORO INDOLE 95.00%
1G
$ 1183.35

American Custom Chemicals Corporation
7-AMINO-4-CHLORO INDOLE 95.00%
5MG
$ 501.28

Alichem
4-Chloro-1H-indol-7-amine
1g
$ 500.50

AK Scientific
4-Chloro-1H-indol-7-amine
1g
$ 1680.00

Aaron Chemicals
1H-Indol-7-amine,4-chloro- 96%
250mg
$ 203.00

Aaron Chemicals
1H-Indol-7-amine,4-chloro- 96%
100mg
$ 127.00

Total 10 raw suppliers

Chemical Property of 4-Chloro-1H-indol-7-amine

Chemical Property:

PSA：41.81000
LogP:2.98470
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:166.0297759
Heavy Atom Count:11
Complexity:151

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-1H-indol-7-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C=CNC2=C1N)Cl

Technology Process of 4-Chloro-1H-indol-7-amine

There total 4 articles about 4-Chloro-1H-indol-7-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96831-52-6
4-chloro-7-nitroindole

: 292636-12-5
4-chloro-7-aminoindole

Guidance literature:: With hydrogen; nickel; In tetrahydrofuran; ethanol; for 6h; under 760 Torr;
DOI:10.1021/jm00107a048

Reference yield:

: 7-azido-4-chloro-1H-indole

: 292636-12-5
4-chloro-7-aminoindole

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; at -40 - 0 ℃;
DOI:10.1016/S0960-894X(00)00219-5

Reference yield:

: 41513-04-6
2-chloro-5-bromonitrobenzene

: 292636-12-5
4-chloro-7-aminoindole

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / -40 °C

2.1: nBuLi / tetrahydrofuran / -70 °C

2.2: TsN₃ / tetrahydrofuran / -70 - -40 °C

3.1: Red-Al / tetrahydrofuran / -40 - 0 °C

With n-butyllithium; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; 1.1: Condensation / 2.1: Metallation / 2.2: Condensation / 3.1: Reduction;
DOI:10.1016/S0960-894X(00)00219-5