Cyclopentanol, 1-[4-(trifluoromethyl)phenyl]-

Base Information

• Chemical Name: Cyclopentanol, 1-[4-(trifluoromethyl)phenyl]-
• CAS No.: 29480-11-3
• Molecular Formula: C12H13F3O
• Molecular Weight: 230.23
• Mol file: 29480-11-3.mol

Synonyms:

Chemical Property of Cyclopentanol, 1-[4-(trifluoromethyl)phenyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanol, 1-[4-(trifluoromethyl)phenyl]-

There total 1 articles about Cyclopentanol, 1-[4-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-trifluoromethylphenyl bromide (402-43-7) + cyclopentanone (120-92-3) → 1-(4-(trifluoromethyl)phenyl)cyclopentan-1-ol (29480-11-3)

Guidance literature:

Multistep reaction; (i) Mg, ether, (ii) /BRN= 605573/;

DOI:10.1021/ja00714a028

Reference yield: 71.0%

1-(4-(trifluoromethyl)phenyl)cyclopentan-1-ol (29480-11-3) → C12H12BrF3O

Guidance literature:

With N-Bromosuccinimide; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; [bis(acetoxy)iodo]benzene; In tetrachloromethane; water; at 20 ℃; for 64h; Irradiation;

DOI:10.1039/C8SC01763H

Reference yield: 68.0%

1-(4-(trifluoromethyl)phenyl)cyclopentan-1-ol (29480-11-3) → 1-(1-hydroperoxycyclopentyl)-4-(trifluoromethyl)benzene

Guidance literature:

With sulfuric acid; dihydrogen peroxide; In dichloromethane; water; at 0 - 25 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1039/d1cc03013b

upstream raw materials:

p-trifluoromethylphenyl bromide

cyclopentanone

Downstream raw materials:

1-(1-Chloro-cyclopentyl)-4-trifluoromethyl-benzene

p-trifluoromethyl-δ-chlorovalerophenone