2-Bromo-9-(phenylsulfanyl)-9H-fluorene

Base Information

• Chemical Name: 2-Bromo-9-(phenylsulfanyl)-9H-fluorene
• CAS No.: 29800-84-8
• Molecular Formula: C19H13BrS
• Molecular Weight: 353.282
• DSSTox Substance ID: DTXSID00503581
• Nikkaji Number: J3.280.218D
• Mol file: 29800-84-8.mol

Synonyms:2-BROMO-9-(PHENYLSULFANYL)-9H-FLUORENE;29800-84-8;DTXSID00503581

Chemical Property of 2-Bromo-9-(phenylsulfanyl)-9H-fluorene

Chemical Property:

• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 351.99213
• Heavy Atom Count: 21
• Complexity: 352

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)SC2C3=CC=CC=C3C4=C2C=C(C=C4)Br

Technology Process of 2-Bromo-9-(phenylsulfanyl)-9H-fluorene

There total 2 articles about 2-Bromo-9-(phenylsulfanyl)-9H-fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,9-dibromo-9H-fluorene (6633-25-6) + thiophenol (108-98-5) → 2-bromo-9-(phenylthio)fluorene (29800-84-8)

Guidance literature:

With sodium methylate; In methanol; overnight;

DOI:10.1021/jo00134a003

Reference yield: 91.0%

2-bromo-9H-fluorene (1133-80-8) + thiophenol (108-98-5) → 2-bromo-9-(phenylthio)fluorene (29800-84-8)

Guidance literature:

With tert.-butylhydroperoxide; potassium hydroxide; In water; dimethyl sulfoxide; at 20 ℃; for 2h; Schlenk technique; Sealed tube; Inert atmosphere; Green chemistry;

DOI:10.1002/ejoc.201801806

Reference yield: 35.0%

2-bromo-9-(phenylthio)fluorene (29800-84-8) → 2-bromo-9-phenylsulfonylfluorene (73838-65-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;

DOI:10.1021/ol300307c

upstream raw materials:

2,9-dibromo-9H-fluorene

thiophenol

2-bromo-9H-fluorene

Downstream raw materials:

2-bromo-9-phenylsulfonylfluorene