Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-

Base Information

Chemical Name:Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-
CAS No.:30077-67-9
Molecular Formula:C11H12N4O
Molecular Weight:216.242
Hs Code.:
ChEMBL ID:CHEMBL56668
DSSTox Substance ID:DTXSID60518737
Nikkaji Number:J360.487J
Wikidata:Q82381543

Synonyms:Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-;30077-67-9;CHEMBL56668;4-((2,4-Diaminopyrimidin-5-yl)methyl)phenol;4-[(2,4-Diaminopyrimidin-5-yl)methyl]phenol;SCHEMBL3937299;DTXSID60518737;BDBM50405986

Suppliers and Price of Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:216.10111102
Heavy Atom Count:16
Complexity:218

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC2=CN=C(N=C2N)N)O

Technology Process of Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-

There total 8 articles about Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 650606-20-5
5-[4-(tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine-2,4-diamine

: 30077-67-9
2,4-diamino-5-(4-hydroxybenzyl)pyrimidine

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃; for 2h;
DOI:10.1016/j.bmc.2003.08.012

Reference yield: 56.0%

: 49873-11-2
5-(4-benzyloxy-benzyl)-pyrimidine-2,4-diamine

: 30077-67-9
2,4-diamino-5-(4-hydroxybenzyl)pyrimidine

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; at 90 - 100 ℃; under 2327.2 Torr;
DOI:10.1021/jm00385a017

Reference yield:

: 4397-53-9
p-benzyloxybenzaldehyde

: 30077-67-9
2,4-diamino-5-(4-hydroxybenzyl)pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 320 g / NaOMe / dimethylsulfoxide; methanol / 0.25 h / 85 °C

2: 57 percent / NaOMe / ethanol / 2 h / Heating

3: 56 percent / H₂, glacial acetic acid / 5percent Pd/C / 90 - 100 °C / 2327.2 Torr

With hydrogen; sodium methylate; acetic acid; palladium on activated charcoal; In methanol; ethanol; dimethyl sulfoxide;
DOI:10.1021/jm00385a017