1,2-Diphenylcyclobutane

Base Information

• Chemical Name: 1,2-Diphenylcyclobutane
• CAS No.: 3018-21-1
• Molecular Formula: C16H16
• Molecular Weight: 208.303
• DSSTox Substance ID: DTXSID00864104
• Nikkaji Number: J126.114B
• Metabolomics Workbench ID: 45130
• Mol file: 3018-21-1.mol

Synonyms:1,2-diphenylcyclobutane;(2-Phenylcyclobutyl)benzene;3018-21-1;Cyclobutane, 1,2-diphenyl-;TRANS-1,2-DIPHENYLCYCLOBUTANE-D5;UNII-413D25991B;styrene dimer SD-4;20071-09-4;trans-1,2-diphenyl cyclobutane;1,3-Diphenyl-Butane;(2-Phenylcyclobutyl)benzene #;DTXSID00864104;CHEBI:151035;AKOS037645165;AS-57885;413D25991B;1,1'-(1,2-Cyclobutanediyl)bisbenzene, 9CI;1,1'-(1-Methyl-1,3-propanediyl)bis-(R)-Benzene

Chemical Property of 1,2-Diphenylcyclobutane

Chemical Property:

• Boiling Point: 309.1±22.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.044±0.06 g/cm3(Predicted)
• LogP: 4.34780
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 208.125200510
• Heavy Atom Count: 16
• Complexity: 184

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C1C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1,2-Diphenylcyclobutane

There total 20 articles about 1,2-Diphenylcyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

cis-1,2-diphenylcyclobutane (7694-30-6) → trans-1,2-diphenylcyclobutane (3018-21-1,7694-30-6,20071-09-4,88243-92-9,88243-93-0)

Guidance literature:

With trifluorormethanesulfonic acid; triethylamine; In dichloromethane; at 0 ℃; for 0.0833333h;

DOI:10.1021/ja00275a073

Reference yield: 58.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → trans-1,2-diphenylcyclobutane (3018-21-1)

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); In dimethyl sulfoxide; N,N-dimethyl-formamide; at 25 ℃; for 12h; diastereoselective reaction; Inert atmosphere; Irradiation;

Reference yield: 13.0%

3,6-diphenyl-3,4,5,6-tetrahydropyrazine (66090-52-6) → 3,6-diphenylpyridazine (891-22-5) + 4-hydroxy-1,4-diphenylbutan-1-one (107487-41-2,7472-58-4) + trans-1,2-diphenylcyclobutane (3018-21-1,7694-30-6,20071-09-4,88243-92-9,88243-93-0) + phenacylacetophenone (495-71-6)

Guidance literature:

With oxygen; In solid; Further byproducts given; Irradiation;

DOI:10.1039/c39900000127

upstream raw materials:

cis-1,2-diphenylcyclobutane

3,6-diphenyl-3,4,5,6-tetrahydropyrazine

meso-1,4-dichloro-1,4-diphenylbutane

1,4-dibromo-1,4-diphenyl-butane

Downstream raw materials:

styrene

(E)-1,2-diphenyl-ethene

ethene

1-phenyl-1,2,3,4-tetrahydronaphthalene