1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo-

Base Information

Chemical Name:1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo-
CAS No.:304465-35-8
Molecular Formula:C18H10N4O3
Molecular Weight:330.302
Hs Code.:
Mol file:304465-35-8.mol

Synonyms:3-cyano-1-p-nitrophenyl-5H-pyrido[3,2-b]indol-2-one;VRX-329747;1-(4-Nitro-phenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile;2,5-dihydro-1-(4- nitro-phenyl)-2-oxo-1H-pyrido[3,2-b]indole-3-carbonitrile;1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile;1-p-nitrophenyl-3-cyano-1,2-dihydropyrido[3,2-b]indolone-2;(1-(4-nitro-phenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile);

Suppliers and Price of 1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo-

Chemical Property:

PSA：107.40000
LogP:3.77508

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo-

There total 6 articles about 1H-Pyrido[3,2-b]indole-3-carbonitrile, 2,5-dihydro-1-(4-nitrophenyl)-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: ethyl α-cyano-β-(3-p-nitrophenylaminoindolyl-2)acrylate

: 304465-35-8
1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile

Guidance literature:: In ethylene glycol; for 0.75h; Heating;
DOI:10.1007/BF02256867

Reference yield: 73.0%

: 167954-14-5
3-[N-(4-nitrophenyl)amino]-2-formylindole

: 304465-35-8
1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile

Guidance literature:: In ethylene glycol; for 2h; Heating / reflux;

Reference yield:

: 33025-60-4
1-(3-hydroxy-1H-indol-1-yl)ethanone

: 304465-35-8
1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetic acid / 5 h / Heating / reflux

2.1: methanol; triethylamine / 4 h / Heating / reflux

3.1: trichlorophosphate / 2.5 h / 0 - 60 °C

3.2: 60 °C

4.1: triethylamine / isopropyl alcohol / 2 h / Heating / reflux

5.1: ethylene glycol / 2 h / Heating / reflux

With methanol; triethylamine; trichlorophosphate; In ethylene glycol; acetic acid; isopropyl alcohol;