2-Methyl-2-heptenal

Base Information

• Chemical Name: 2-Methyl-2-heptenal
• CAS No.: 30567-26-1
• Molecular Formula: C8H14O
• Molecular Weight: 126.19600
• Hs Code.: 2912190090
• Mol file: 30567-26-1.mol

Synonyms:2-Heptenal, 2-methyl-;2-Methylhept-2-ene-1-one;2-Heptenal,2-methyl;

Chemical Property of 2-Methyl-2-heptenal

Chemical Property:

• Melting Point: 3.5°C (estimate)
• Refractive Index: 1.4353 (estimate)
• Boiling Point: 184.35°C (estimate)
• PSA: 17.07000
• Density: 0.8654 (estimate)
• LogP: 2.32180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-2-heptenal

There total 15 articles about 2-Methyl-2-heptenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

α,α-bis(trimethylsilyl)-tert-butylpropionaldimine (147227-25-6) + pentanal (110-62-3) → (E)-2-methyl-hept-2-enal (30567-26-1)

Guidance literature:

α,α-bis(trimethylsilyl)-tert-butylpropionaldimine; pentanal; With zinc dibromide; In tetrahydrofuran; at 20 ℃; for 6h;

With water; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.jorganchem.2006.03.015

Reference yield: 82.0%

trans 3-hepten-2-one (5609-09-6) + Chloroiodomethane (593-71-5) → (2Z)-2-methyl-2-heptenal (30567-26-1,56161-68-3)

Guidance literature:

With trimethylsilylmethyllithium; lithium bromide; In tetrahydrofuran; pentane; at -78 - 20 ℃;

DOI:10.1002/anie.201706236

Reference yield: 79.0%

pentanal (110-62-3) + (Z)-2-Trimethylsilanyl-1-trimethylsilanyloxy-propene (154581-92-7) → (E)-2-methyl-hept-2-enal (30567-26-1)

Guidance literature:

trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 3h;

DOI:10.1016/S0040-4039(00)61554-X

upstream raw materials:

trans 3-hepten-2-one

Chloroiodomethane

2-bromo-2-methyl-heptanal

diethyl-dithiocarbamic acid 3-butyl-2-methyl-prop-1-ene-1,3-diyl ester

Downstream raw materials:

(E)-6-methyl-1-phenylundec-6-en-3-yn-5-yl acetate

(E)-1-(3-butyl-4-methyl-2-oxocyclopent-3-enylidene)-3-phenylpropyl acetate

(Z)-1-(3-butyl-4-methyl-2-oxocyclopent-3-enylidene)-3-phenylpropyl acetate

Refernces

• 1、 Rountree, Sandra M.,Taylor, Sarah F.R.,Hardacre, Christopher,Lagunas, M. Cristina,Davey, Paul N.. "Synthesis of α,β-unsaturated aldehydes and nitriles via cross-metathesis reactions using Grubbs' catalysts". . p. 94 - 104. Retrieved 2015/09/28.
• 2、 Lahmar, Nour,Aatar, Jamaa,Ayed, Ta?cir Ben,Amri, Hassen,Bellassoued, Moncef. "A general route to α-alkyl (E)-α,β-unsaturated aldehydes". . p. 3018 - 3026. Retrieved 2007/10/03.