Technology Process of 9-Acridinol, 9,10-dihydro-10-methyl-
There total 8 articles about 9-Acridinol, 9,10-dihydro-10-methyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium sulfate; scandium tris(trifluoromethanesulfonate);
In
N,N-dimethyl-formamide;
at 100 ℃;
for 5h;
Schlenk technique;
Inert atmosphere;
Green chemistry;
DOI:10.1021/ol400371h
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: copper diacetate; sodium acetate / water / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / Cooling with ice
2.2: 2 h / 80 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C
4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 3 h / 100 °C
5.1: scandium tris(trifluoromethanesulfonate); sodium sulfate / N,N-dimethyl-formamide / 5 h / 100 °C / Schlenk technique; Inert atmosphere; Green chemistry
With
lithium aluminium tetrahydride; copper diacetate; sodium acetate; sodium hydride; sodium sulfate; scandium tris(trifluoromethanesulfonate); 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ol400371h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 3 h / 100 °C
2: scandium tris(trifluoromethanesulfonate); sodium sulfate / N,N-dimethyl-formamide / 5 h / 100 °C / Schlenk technique; Inert atmosphere; Green chemistry
With
sodium sulfate; scandium tris(trifluoromethanesulfonate); 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ol400371h
