Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-

Base Information

Chemical Name:Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-
CAS No.:309254-00-0
Molecular Formula:C16H17N
Molecular Weight:223.318
Hs Code.:
DSSTox Substance ID:DTXSID20465450
Nikkaji Number:J1.358.908I

Synonyms:309254-00-0;Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-;DTXSID20465450

Suppliers and Price of Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:223.136099547
Heavy Atom Count:17
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(N1CC2=CC=CC=C2)C3=CC=CC=C3
Isomeric SMILES:C[C@H]1[C@H](N1CC2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)-

There total 4 articles about Aziridine, 2-methyl-3-phenyl-1-(phenylmethyl)-, (2S,3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 309253-96-1
(1S,2S)-(+)-(E)-N-(benzylidene)-1-chloro-1-phenyl-2-propylamine

: 309254-00-0
(-)-(2S,3R)-cis-1-benzyl-2-methyl-3-phenylaziridine

Guidance literature:: With sodium tetrahydroborate; In methanol; for 1h; Heating;
DOI:10.1016/S0040-4020(00)00627-X

Reference yield: 57.0%

: 1485-13-8,7763-71-5,13148-30-6,13452-28-3,20993-60-6,61091-40-5,61091-41-6
(-)-(2S,3R)-cis-2-methyl-3-phenylaziridine

: 100-44-7
benzyl chloride

: 309254-00-0
(-)-(2S,3R)-cis-1-benzyl-2-methyl-3-phenylaziridine

Guidance literature:: With n-butyllithium; In tetrahydrofuran;
DOI:10.1002/ejic.200300503

Reference yield:

: 492-41-1,58550-13-3,757124-50-8
(1R,2S)-norephedrine

: 309254-00-0
(-)-(2S,3R)-cis-1-benzyl-2-methyl-3-phenylaziridine

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / PCl₅ / CHCl₃ / Heating

2: 88 percent / triethylamine; magnesium sulfate / CH₂Cl₂ / 1 h / Heating

3: 99 percent / sodium borohydride / methanol / 1 h / Heating

With sodium tetrahydroborate; phosphorus pentachloride; magnesium sulfate; triethylamine; In methanol; dichloromethane; chloroform;
DOI:10.1016/S0040-4020(00)00627-X