DiazepaM IMpurity F

Base Information

• Chemical Name: DiazepaM IMpurity F
• CAS No.: 31269-33-7
• Molecular Formula: C16H13ClN2O
• Molecular Weight: 284.74000
• Mol file: 31269-33-7.mol

Synonyms:Diazepam Impurity F (BP);DIAZEPAM IMPURITY F;7-Chlor-2-methoxy-5-phenyl-3H-benzodiazepin;7-Chlor-2-methoxy-5-phenyl-3H-1,4-benzodiazepin;

Chemical Property of DiazepaM IMpurity F

Chemical Property:

• Melting Point: 86-88 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 416.7±55.0 °C(Predicted)
• PKA: 1.99±0.20(Predicted)
• PSA: 33.95000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 2.73860

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DiazepaM IMpurity F

There total 2 articles about DiazepaM IMpurity F which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-morpholin-4-yl-phosphinic acid 7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester (59318-11-5) → 7-chloro-2-methoxy-5-phenyl-3H-1,4-benzodiazepine (31269-33-7)

Guidance literature:

With sodium methylate; In methanol;

Reference yield:

→ 7-chloro-2-methoxy-5-phenyl-3H-1,4-benzodiazepine (31269-33-7)

Guidance literature:

7-Chlor-2-methoxy-5-phenyl-5H-1,4-benzodiazepin (8);

upstream raw materials:

di-morpholin-4-yl-phosphinic acid 7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester