Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate

Base Information

Chemical Name:Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
CAS No.:31430-19-0
Molecular Formula:C17H15N3O3
Molecular Weight:309.324
Hs Code.:
UNII:5A8Z137Y72
DSSTox Substance ID:DTXSID30185354
Nikkaji Number:J2.981.074E
Wikidata:Q27261743
Mol file:31430-19-0.mol

Synonyms:31430-19-0;Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate;o-Desmethyl-O-ethyl mebendazole;UNII-5A8Z137Y72;Mebendazole Ethyl Ester;5A8Z137Y72;Mebendazole specified impurity E [EP];Carbamic acid, N-(6-benzoyl-1H-benzimidazol-2-yl)-, ethyl ester;SCHEMBL24209313;DTXSID30185354;FT-0670958;MEBENDAZOLE IMPURITY E [EP IMPURITY];ethyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate;Q27261743;N-(6-Benzoyl 1H-benzoimidazole-2-yl)carbamic acid ethyl ester;Ethyl (5-Benzoyl-1H-benzimidazol-2-yl)carbamate;Mebendazole Imp. E (EP);Mebendazole Related Compound E;Mebendazole Impurity E

Suppliers and Price of Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Mebendazole ethyl ester
250mg
$ 468.00

TRC
MebendazoleEthylAnalog
500mg
$ 185.00

Medical Isotopes, Inc.
MebendazoleEthylAnalog
500 mg
$ 650.00

American Custom Chemicals Corporation
MEBENDAZOLE EP IMPURITY E 95.00%
5MG
$ 451.30

Total 11 raw suppliers

Chemical Property of Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate

Chemical Property:

Melting Point:>299°C (dec.)
PKA:9.97±0.10(Predicted)
PSA：87.57000
Density:1.349±0.06 g/cm3(Predicted)
LogP:3.37590
Storage Temp.:Amber Vial, Refrigerator
Solubility.:DMSO (Slightly, Heated)
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:309.11134135
Heavy Atom Count:23
Complexity:437

Purity/Quality:

99%, ^*data from raw suppliers

Mebendazole ethyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
Uses Mebendazole (M200500) metabolite.

Technology Process of Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate

There total 2 articles about Ethyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1320358-37-9
C₁₇H₁₇N₃O₃S

: 31430-19-0
(5-benzoyl-1⁽³⁾H-benzoimidazol-2-yl)-carbamic acid ethyl ester

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃;
DOI:10.1016/j.tetlet.2011.05.146