1,3-Bis(4-aminophenyl)propane

Base Information

• Chemical Name: 1,3-Bis(4-aminophenyl)propane
• CAS No.: 2767-73-9
• Molecular Formula: C15H18 N2
• Molecular Weight: 226.321
• NSC Number: 86415
• DSSTox Substance ID: DTXSID60950315
• Nikkaji Number: J744.455I
• Wikidata: Q82928314
• Mol file: 2767-73-9.mol

Synonyms:1,3-bis(4-aminophenyl)propane;2767-73-9;4-[3-(4-aminophenyl)propyl]aniline;Benzenamine, 4,4'-(1,3-propanediyl)bis-;NSC86415;SCHEMBL421341;DTXSID60950315;AC9230;MFCD30580616;NSC-86415;4,4'-(Propane-1,3-diyl)dianiline;SY253849

Chemical Property of 1,3-Bis(4-aminophenyl)propane

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 226.146998583
• Heavy Atom Count: 17
• Complexity: 179

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CCCC2=CC=C(C=C2)N)N

Technology Process of 1,3-Bis(4-aminophenyl)propane

There total 2 articles about 1,3-Bis(4-aminophenyl)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-bis-(4-nitro-phenyl)-propane (10368-11-3) → 1,3-bis-(4-amino-phenyl)-propane (2767-73-9)

Guidance literature:

With 1,4-dioxane; nickel; hydrazine hydrate;

DOI:10.1021/jo01097a608

Reference yield:

1,3-diphenylpropane (1081-75-0) → 1,3-bis-(4-amino-phenyl)-propane (2767-73-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; acetic acid anhydride; HNO₃

2: N₂H₄+H₂O; Raney nickel; dioxane

With 1,4-dioxane; sulfuric acid; nitric acid; acetic anhydride; nickel; hydrazine hydrate;

DOI:10.1021/jo01097a608

Reference yield: 74.0%

1,3-bis-(4-amino-phenyl)-propane (2767-73-9) + acetic anhydride (108-24-7) → N,N’-(propane-1,3-diylbis(2-nitro-4,1-phenylene))diacetamide

Guidance literature:

With toluene-4-sulfonic acid; potassium nitrate; at 20 ℃; Cooling with ice;

DOI:10.1080/10610278.2021.1917768

upstream raw materials:

1,3-bis-(4-nitro-phenyl)-propane

1,3-diphenylpropane

Downstream raw materials:

C₄₁H₄₄N₄O₄