2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-

Base Information

Chemical Name:2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-
CAS No.:31639-15-3
Molecular Formula:C11H12ClNS
Molecular Weight:225.742
Hs Code.:
DSSTox Substance ID:DTXSID90395270
Mol file:31639-15-3.mol

Synonyms:31639-15-3;2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-;DTXSID90395270

Suppliers and Price of 2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:225.0378983
Heavy Atom Count:14
Complexity:217

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C=CC(=S)C1=CC=C(C=C1)Cl

Technology Process of 2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)-

There total 5 articles about 2-Propene-1-thione, 1-(4-chlorophenyl)-3-(dimethylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 7089-20-5
[3-chloro-3-(4-chloro-phenyl)-allylidene]-dimethyl-ammonium; perchlorate

: 31639-15-3
(E)-1-(4-Chloro-phenyl)-3-dimethylamino-propenethione

Guidance literature:: With sodium sulfide; In water; N,N-dimethyl-formamide; for 2h; Ambient temperature;
DOI:10.1021/jo01312a011

Reference yield:

: 28587-05-5
3-dimethylamino-1(4-chloro-phenyl)-2-propen-1-one

: 31639-15-3
(E)-1-(4-Chloro-phenyl)-3-dimethylamino-propenethione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Phosphorus oxychloride, 2.) Sodium perchlorate monohydrate / 1.) anhydr. Dichloromethane, room temp., 20 min; 0 deg C, 10 min, 2.) Dichloromethane/water, 0 deg C, 20 min

2: 68 percent / Sodium sulfide nonahydrate / dimethylformamide; H₂O / 2 h / Ambient temperature

With sodium sulfide; sodium perchlorate; trichlorophosphate; In water; N,N-dimethyl-formamide;
DOI:10.1021/jo01312a011

Reference yield:

: 99-91-2
para-chloroacetophenone

: 31639-15-3
(E)-1-(4-Chloro-phenyl)-3-dimethylamino-propenethione

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / 20 h / Heating

2: 1.) Phosphorus oxychloride, 2.) Sodium perchlorate monohydrate / 1.) anhydr. Dichloromethane, room temp., 20 min; 0 deg C, 10 min, 2.) Dichloromethane/water, 0 deg C, 20 min

3: 68 percent / Sodium sulfide nonahydrate / dimethylformamide; H₂O / 2 h / Ambient temperature

With sodium sulfide; sodium perchlorate; trichlorophosphate; In water; N,N-dimethyl-formamide;
DOI:10.1021/jo01312a011