(2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol

Base Information

Chemical Name:(2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol
CAS No.:317319-27-0
Molecular Formula:C12H9F4NOS
Molecular Weight:291.26500
Hs Code.:2934100090
DSSTox Substance ID:DTXSID00594813
Wikidata:Q82489721
Mol file:317319-27-0.mol

Synonyms:317319-27-0;(2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol;2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-hydroxymethyl Thiazole;{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol;[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methanol;SCHEMBL5017176;DTXSID00594813;MFCD07369416;AKOS005072956;HA-0834;5-(Hydroxymethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazole;DB-260573;CS-0450944;J-500515;[2-(3-fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-yl]-methanol

Suppliers and Price of (2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-hydroxymethylThiazole
10mg
$ 80.00

SynQuest Laboratories
5-(Hydroxymethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazole
500 mg
$ 295.00

Medical Isotopes, Inc.
2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-hydroxymethylThiazole
125 mg
$ 1880.00

Matrix Scientific
{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol >95%
5g
$ 1384.00

Matrix Scientific
{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol >95%
1g
$ 603.00

Matrix Scientific
{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol >95%
500mg
$ 486.00

Crysdot
(2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol 95+%
1g
$ 455.00

Chemenu
{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol 95%
1g
$ 430.00

Apolloscientific
5-(Hydroxymethyl)-2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazole
500mg
$ 184.00

American Custom Chemicals Corporation
5-(HYDROXYMETHYL)-2-[3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]-4-METHYL-1,3-THIAZOLE 95.00%
5G
$ 1712.87

Total 11 raw suppliers

Chemical Property of (2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol

Chemical Property:

Melting Point:159-161
PSA：61.36000
LogP:3.76870
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:291.03409773
Heavy Atom Count:19
Complexity:315

Purity/Quality:

98%min ^*data from raw suppliers

2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-hydroxymethylThiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC(=N1)C2=CC(=C(C=C2)C(F)(F)F)F)CO
Uses 2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-hydroxymethyl Thiazole (cas# 317319-27-0) is a compound useful in organic synthesis.

Technology Process of (2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol

There total 2 articles about (2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 317319-21-4
ethyl 4-methyl-2-[3-fluoro-4-(trifluoromethyl)phenyl]thiazole-5-carboxylate

: 317319-27-0
5-hydroxymethyl-4-methyl-2-[3-fluoro-4-(trifluoromethyl)phenyl]thiazole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0960-894X(03)00207-5

Reference yield:

: 317319-16-7
3-fluoro-4-(trifluoromethyl)thiobenzamide

: 317319-27-0
5-hydroxymethyl-4-methyl-2-[3-fluoro-4-(trifluoromethyl)phenyl]thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / ethanol / Heating

2: 87 percent / LiAlH₄ / tetrahydrofuran / 20 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(03)00207-5