1,3-Benzenediamine, 2-methoxy-

Base Information

• Chemical Name: 1,3-Benzenediamine, 2-methoxy-
• CAS No.: 32114-60-6
• Molecular Formula: C7H10N2O
• Molecular Weight: 138.169
• DSSTox Substance ID: DTXSID70953993
• Nikkaji Number: J805.034A
• Wikidata: Q82932981
• Mol file: 32114-60-6.mol

Synonyms:2-methoxybenzene-1,3-diamine;32114-60-6;1,3-Benzenediamine, 2-methoxy-;2,6-Diaminoanisole;N-o-anisidylimine;SCHEMBL358326;2-methoxy-benzene-1,3-diamine;DTXSID70953993;PAXOFIORPRCXBV-UHFFFAOYSA-N;AKOS006339261;AS-56943;CS-0161381

Chemical Property of 1,3-Benzenediamine, 2-methoxy-

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 138.079312947
• Heavy Atom Count: 10
• Complexity: 97.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC=C1N)N

Technology Process of 1,3-Benzenediamine, 2-methoxy-

There total 3 articles about 1,3-Benzenediamine, 2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,6-dinitroanisole (3535-67-9) → 2-methoxybenzene-1,3-diamine (32114-60-6)

Guidance literature:

With ammonium chloride; zinc; In water; for 2.5h; Heating / reflux;

Reference yield:

1-chloro-2,6-dinitrobenzene (606-21-3) → 2-methoxybenzene-1,3-diamine (32114-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 20 °C

2: hydrogen / palladium 10% on activated carbon / ethanol / 760.05 Torr

With methanol; hydrogen; palladium 10% on activated carbon; In ethanol;

Reference yield:

2-bromo-1,3-dinitrobenzene (4185-79-9) → 2-methoxybenzene-1,3-diamine (32114-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium / 20 °C / Inert atmosphere; Schlenk technique

2: tin(II) chloride dihdyrate / ethanol / 1.5 h / 70 °C / Inert atmosphere

With tin(II) chloride dihdyrate; sodium; In ethanol;

DOI:10.1021/om400114h

upstream raw materials:

2,6-dinitroanisole

1-chloro-2,6-dinitrobenzene

2-bromo-1,3-dinitrobenzene

Downstream raw materials:

N-[3-(Ethoxyoxalyl-amino)-2-methoxy-phenyl]-oxalamic acid ethyl ester

ethyl-2,6-diamino-(N,N,N',N'-tetraacetate)anisole

1,1'-(2-methoxy-1,3-phenylene)bis(2,5-diisopropylpyrrolyl)

1,1'-(2-methoxy-1,3-phenylene)bis(2,5-diphenylpyrrolyl)