(S)-6-Hydroxynicotine

Base Information

Chemical Name:(S)-6-Hydroxynicotine
CAS No.:10516-09-3
Molecular Formula:C10H14 N2 O
Molecular Weight:178.23
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20331409
Nikkaji Number:J38.661H
Wikidata:Q27102445
Metabolomics Workbench ID:50950
Mol file:10516-09-3.mol

Synonyms:(S)-6-Hydroxynicotine;l-6-Hydroxynicotine;10516-09-3;(S)-6-Hydroxy Nicotine;5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-2-ol;(S)-5-(1-Methylpyrrolidin-2-yl)pyridin-2(1H)-one;(S)-5-(1-methyl-pyrrolidin-2-yl)-pyridin-2-ol;(S)-5-(1-methyl-pyrrolidin-2-yl)-1H-pyridin-2-one;5-[(2S)-1-methylpyrrolidin-2-yl]-1H-pyridin-2-one;HNL;6-hydroxy-L-nicotine;SCHEMBL418278;5-[(2S)-1-Methyl-2-pyrrolidinyl]-2(1H)-pyridinone;SCHEMBL9414172;CHEBI:17532;DTXSID20331409;C01056;J-001350;Q27102445;5-[(2S)-1-methylpyrrolidin-2-yl]-1,2-dihydropyridin-2-one

Suppliers and Price of (S)-6-Hydroxynicotine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-6-HydroxyNicotine
2mg
$ 125.00

American Custom Chemicals Corporation
(S)-6-HYDROXY NICOTINE 95.00%
5MG
$ 503.98

Total 7 raw suppliers

Chemical Property of (S)-6-Hydroxynicotine

Chemical Property:

Boiling Point:372.8±42.0 °C(Predicted)
PKA:11.98±0.10(Predicted)
PSA：36.10000
Density:1.135±0.06 g/cm3(Predicted)
LogP:1.07950
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:281

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-6-HydroxyNicotine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC1C2=CNC(=O)C=C2
Isomeric SMILES:CN1CCC[C@H]1C2=CNC(=O)C=C2
Uses A metabolite of NIcotine (N412450). Carcinogen. (S)-6-Hydroxy Nicotinev is a metabolite of Nicotine (N412450), a carcinogen agent.

Technology Process of (S)-6-Hydroxynicotine

There total 3 articles about (S)-6-Hydroxynicotine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 2055-13-2
5-(N'-Methyl-2'-pyrrolidinyl)-2-hydroxy pyridine

: 10516-09-3
(S)-6-hydroxy-D-nicotine

Guidance literature:: With borane-ammonia complex; 6-hydroxy-D-nicotine oxidase; for 1h; Reagent/catalyst; enantioselective reaction; Kinetics; Enzymatic reaction;
DOI:10.1002/cctc.201301008