1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE

Base Information

Chemical Name:1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE
CAS No.:324785-29-7
Molecular Formula:C15H20ClNO3
Molecular Weight:297.782
Hs Code.:
Mol file:324785-29-7.mol

Synonyms:3-(4-chloro-phenyl)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;1-Boc-3-(4-chlorophenyl)-3-hydroxypyrrolidine;

Suppliers and Price of 1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 95+%
250mg
$ 547.00

Crysdot
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 95+%
100mg
$ 342.00

Crysdot
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 95+%
1g
$ 1369.00

Chemenu
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 95%
1g
$ 1290.00

Alichem
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate
250mg
$ 568.56

Alichem
tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate
1g
$ 1380.00

Acrotein
1-Boc-3-(4-chlorophenyl)-3-hydroxypyrrolidine 97%
0.25g
$ 146.67

ACHEMBLOCK
1-Boc-3-(4-chlorophenyl)-3-hydroxypyrrolidine 95%
250MG
$ 180.00

Total 6 raw suppliers

Chemical Property of 1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE

Chemical Property:

PSA：49.77000
LogP:3.10630

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE

There total 5 articles about 1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 873-77-8
(4-chlorphenyl)magnesium bromide

: 101385-93-7
3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester

: 324785-29-7
tert-butyl 3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate

Guidance literature:: (4-chlorphenyl)magnesium bromide; 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester; In tetrahydrofuran; diethyl ether; at 20 ℃;

With water; ammonium chloride; In tetrahydrofuran; diethyl ether;

Reference yield: 42.9%

: 106-39-8
bromochlorobenzene

: 101385-93-7
3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester

: 324785-29-7
tert-butyl 3-(4-chlorophenyl)-3-hydroxypyrrolidine-1-carboxylate

Guidance literature:: bromochlorobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃;

3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester; In tetrahydrofuran; at -78 ℃; for 2h;

With ammonium chloride; In tetrahydrofuran; water;