6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS No.:96719-51-6
Molecular Formula:C₂₃H₂₃NO₂
Molecular Weight:345.441
Hs Code.:
DSSTox Substance ID:DTXSID80914373

Synonyms:96719-51-6;6-METHOXY-1-(2-METHOXYPHENYL)-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE;1,2,3,4-Tetrahydro-6-methoxy-1-(2-methoxyphenyl)-2-phenylisoquinoline;Isoquinoline, 1,2,3,4-tetrahydro-6-methoxy-1-(2-methoxyphenyl)-2-phenyl-;DTXSID80914373;LS-85988

Suppliers and Price of 6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Vapor Pressure:3.7E-10mmHg at 25°C
Boiling Point:500.7°C at 760 mmHg
Flash Point:169.4°C
Density:1.137g/cm³
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:345.172878976
Heavy Atom Count:26
Complexity:436

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(N(CC2)C3=CC=CC=C3)C4=CC=CC=C4OC

Technology Process of 6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline

There total 6 articles about 6-Methoxy-1-(2-methoxyphenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96719-18-5
6-Methoxy-1-(2-methoxy-phenyl)-2-phenyl-3,4-dihydro-isoquinolinium; iodide

: 96719-51-6
6-Methoxy-1-(2-methoxy-phenyl)-2-phenyl-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: With sodium tetrahydroborate; In methanol; Yield given;

Reference yield:

: 1798-09-0
m-methoxyphenylacetic acid

: 96719-51-6
6-Methoxy-1-(2-methoxy-phenyl)-2-phenyl-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: Multi-step reaction with 6 steps

1: SOCl₂ / benzene / 1 h / Heating

2: diethyl ether / Ambient temperature

3: 74 percent / LAH / dioxane; diethyl ether

4: 1.) SOCl₂ / 1.) benzene, reflux, 2.) ether, r.t.

5: 1.) POCl₃, 2.) KI / 1.) reflux, 2.) H₂O

6: NaBH₄ / methanol

With sodium tetrahydroborate; lithium aluminium tetrahydride; thionyl chloride; potassium iodide; trichlorophosphate; In 1,4-dioxane; methanol; diethyl ether; benzene;

Reference yield:

: 51009-27-9
[2-(3-Methoxy-phenyl)-ethyl]-phenyl-amine

: 96719-51-6
6-Methoxy-1-(2-methoxy-phenyl)-2-phenyl-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) SOCl₂ / 1.) benzene, reflux, 2.) ether, r.t.

2: 1.) POCl₃, 2.) KI / 1.) reflux, 2.) H₂O

3: NaBH₄ / methanol

With sodium tetrahydroborate; thionyl chloride; potassium iodide; trichlorophosphate; In methanol;