L-ERYTHRO-4-FLUOROGLUTAMIC ACID

Base Information

Chemical Name:L-ERYTHRO-4-FLUOROGLUTAMIC ACID
CAS No.:32563-24-9
Molecular Formula:C5H8FNO4
Molecular Weight:165.121
Hs Code.:2922499990
Mol file:32563-24-9.mol

Synonyms:Norisoboidine;Norboldine;Laurolistine;L-Threo-4-Fluoroglutamic Acid;

Suppliers and Price of L-ERYTHRO-4-FLUOROGLUTAMIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
L-ERYTHRO-4-FLUOROGLUTAMIC ACID 95.00%
10MG
$ 702.19

Total 10 raw suppliers

Chemical Property of L-ERYTHRO-4-FLUOROGLUTAMIC ACID

Chemical Property:

Vapor Pressure:1.37E-05mmHg at 25°C
Melting Point:179-180oC
Boiling Point:342.4oC at 760 mmHg
Flash Point:160.9oC
PSA：100.62000
Density:1.498g/cm3
LogP:-0.08860

Purity/Quality:

98%min ^*data from raw suppliers

L-ERYTHRO-4-FLUOROGLUTAMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-ERYTHRO-4-FLUOROGLUTAMIC ACID

There total 19 articles about L-ERYTHRO-4-FLUOROGLUTAMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 393810-25-8,95048-75-2,95048-76-3
(2S,4R)-4-fluoro-5-oxo-pyrrolidine-2-carboxylic acid methyl ester

: 32563-24-9,149117-03-3,91383-48-1,91383-47-0
(2S,4R)-L-erythro-4-fluoroglutamic acid

Guidance literature:: (2S,4R)-4-fluoro-5-oxo-pyrrolidine-2-carboxylic acid methyl ester; With hydrogenchloride; In water; for 4h; Heating;

With methyloxirane; In ethanol; at 0 ℃; for 0.333333h; Further stages.;
DOI:10.1021/jo0106804

Reference yield: 16.1%

: 149033-38-5
Methyl 1-acetyl-trans-4-fluoro-D-pyrrolidin-5-one-2-carboxylate

: 32563-24-9,149117-03-3,91383-48-1,91383-47-0
(2S,4R)-L-erythro-4-fluoroglutamic acid

Guidance literature:: With hydrogenchloride; for 4h; Heating;
DOI:10.1016/S0022-1139(00)80034-2

Reference yield:

: 64187-47-9
1-benzyloxycarbonyl-4-keto-L-proline

: 32563-24-9,149117-03-3,91383-48-1,91383-47-0
(2S,4R)-L-erythro-4-fluoroglutamic acid

Guidance literature:: Multi-step reaction with 5 steps

1: NaBH₄

2: HBr, AcOH

4: 1) DAST, 2) RuO₄

5: 1) HCl, 2) Ag₂O

With hydrogenchloride; sodium tetrahydroborate; ruthenium tetroxide; hydrogen bromide; acetic acid; 4,4'-diaminostilbene-2,2'-disulfonic acid; silver(l) oxide;
DOI:10.1016/S0022-1139(00)83705-7