N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid

Base Information

• Chemical Name: N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid
• CAS No.: 6687-40-7
• Molecular Formula: C₄₂H₆₃N₇O₈S
• Molecular Weight: 826.07

Synonyms:

Chemical Property of N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid

There total 3 articles about N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) → N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid (6687-40-7)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) ClCO₂Et, nBu₃N, THF, (ii) /BRN= 2978781/

2: (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py

Reference yield:

Hcy(Bzl)-NH2 (6687-37-2) → N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid (6687-40-7)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) ClCO₂Et, nBu₃N, THF, (ii) /BRN= 2978781/

2: (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py

Reference yield:

Boc-Ala-Phe-Ile-Gly-OH (3235-90-3) + N-Carbo-tert.-butoxy-Leu--homocystein-amid (6687-38-3) → N-tert.-Butyloxycarbonyl-Ala-Phe-Ile-Gly-Leu--homocystein-amid (6687-40-7)

Guidance literature:

Multistep reaction; (i) HCl, AcOH, (ii) /BRN= 5681424/, DCC, Py;

upstream raw materials:

Boc-Ala-Phe-Ile-Gly-OH

N-Carbo-tert.-butoxy-Leu--homocystein-amid

N-tert-butoxycarbonyl-L-leucine

Hcy(Bzl)-NH₂

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