(3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Base Information

Chemical Name:(3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone
CAS No.:329944-59-4
Molecular Formula:C14H9BrCl2O2
Molecular Weight:360.034
Hs Code.:2914700090
European Community (EC) Number:608-814-3
DSSTox Substance ID:DTXSID40470884
Wikidata:Q82299086
Mol file:329944-59-4.mol

Synonyms:329944-59-4;(3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone;(3-bromo-5-chlorophenyl)-(5-chloro-2-methoxyphenyl)methanone;(3-BROMO-5-CHLORO-PHENYL)-(5-CHLORO-2-METHOXY-PHENYL)-METHANONE;AGN-PC-00EGB3;SCHEMBL4729562;DTXSID40470884;AKOS015965512

Suppliers and Price of (3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3-BROMO-5-CHLORO-PHENYL)-(5-CHLORO-2-METHOXY-PHENYL)-METHANONE 95.00%
5MG
$ 503.02

Alichem
(3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone
1g
$ 998.00

Total 6 raw suppliers

Chemical Property of (3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
PSA：26.30000
LogP:4.99550
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:357.91630
Heavy Atom Count:19
Complexity:327

Purity/Quality:

≥99% ^*data from raw suppliers

(3-BROMO-5-CHLORO-PHENYL)-(5-CHLORO-2-METHOXY-PHENYL)-METHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Cl)C(=O)C2=CC(=CC(=C2)Br)Cl

Technology Process of (3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

There total 5 articles about (3-Bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 187396-78-7
5-chloro-N,2-dimethoxy-N-methylbenzamide

: 14862-52-3
1,3-dibromo-5-chlorobenzene

: 329944-59-4
(3-bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Guidance literature:: 1,3-dibromo-5-chlorobenzene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.166667h;

5-chloro-N,2-dimethoxy-N-methylbenzamide; In diethyl ether; hexane; at -78 - 20 ℃; for 15.25h;
DOI:10.1021/jm050670l

Reference yield: 64.0%

: 329944-59-4
(3-bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Guidance literature:

Reference yield:

: 3438-16-2
5-chloro-2-methoxybenzoic acid

: 329944-59-4
(3-bromo-5-chlorophenyl)(5-chloro-2-methoxyphenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: oxalyl chloride; DMF / CH₂Cl₂ / 21 h / 20 °C

2.1: 4.265 g / Et₃N / CHCl₃ / 2.5 h / 0 - 20 °C

3.1: n-BuLi / diethyl ether; hexane / 0.17 h / -78 °C

3.2: 97 percent / diethyl ether; hexane / 15.25 h / -78 - 20 °C

With n-butyllithium; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In diethyl ether; hexane; dichloromethane; chloroform;
DOI:10.1021/jm050670l