6-(Trifluoromethyl)-9H-purin-2-amine

Base Information

Chemical Name:6-(Trifluoromethyl)-9H-purin-2-amine
CAS No.:2993-20-6
Molecular Formula:C₆H₄F₃N₅
Molecular Weight:203.126
Hs Code.:
NSC Number:515515
DSSTox Substance ID:DTXSID60901448
Nikkaji Number:J457.116I
Mol file:2993-20-6.mol

Synonyms:6-(Trifluoromethyl)-9H-purin-2-amine;2993-20-6;6-(trifluoromethyl)-7H-purin-2-amine;SCHEMBL5508786;DTXSID60901448;BPGSASFKCZQNNZ-UHFFFAOYSA-N;NSC515515;AKOS000320371;AKOS037505787;NSC-515515;SB78413

Suppliers and Price of 6-(Trifluoromethyl)-9H-purin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
6-(trifluoromethyl)-9H-Purin-2-amine 97.00%
25G
$ 4010.00

AccelPharmtech
6-(trifluoromethyl)-9H-Purin-2-amine 97.00%
5G
$ 2610.00

AccelPharmtech
6-(trifluoromethyl)-9H-Purin-2-amine 97.00%
1G
$ 1940.00

Total 7 raw suppliers

Chemical Property of 6-(Trifluoromethyl)-9H-purin-2-amine

Chemical Property:

Vapor Pressure:0.0758mmHg at 25°C
Boiling Point:227.8°C at 760 mmHg
Flash Point:91.6°C
PSA：80.48000
Density:1.99g/cm³
LogP:1.53510
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:203.04187964
Heavy Atom Count:14
Complexity:220

Purity/Quality:

99% ^*data from raw suppliers

6-(trifluoromethyl)-9H-Purin-2-amine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=NC(=NC(=C2N1)C(F)(F)F)N

Technology Process of 6-(Trifluoromethyl)-9H-purin-2-amine

There total 9 articles about 6-(Trifluoromethyl)-9H-purin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 222532-18-5
9-(Tetrahydropyran-2-yl)-2-<(tetrahydropyran-2-yl)amino>-6-(trifluoromethyl)purine

: 2993-20-6
2-Amino-6-(trifluoromethyl)purine

Guidance literature:: With Dowex 50 X 8 (H(+)); water; In methanol; for 1h; Heating;
DOI:10.1135/cccc19990229

Reference yield:

: 2927-10-8
6-trifluoromethyl-pyrimidine-2,4,5-triamine

: 2993-20-6
6-trifluoromethyl-7(9)H-purin-2-ylamine

Guidance literature:: With formamide;
DOI:10.1021/jo01083a607 DOI:10.1021/ja01554a041

Reference yield:

: 2-amino-6-trifluoromethyl-pyrimidine-4,5-dione-5-phenylhydrazone

: 2993-20-6
6-trifluoromethyl-7(9)H-purin-2-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: NH₃; POCl₃

2: palladium/charcoal; ethanol / Hydrogenation

3: formic acid

With palladium on activated charcoal; formic acid; ethanol; ammonia; trichlorophosphate;
DOI:10.1021/ja01554a041