Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-

Base Information

Chemical Name:Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-
CAS No.:96825-89-7
Molecular Formula:C₂₁H₁₈N₄O
Molecular Weight:342.4
Hs Code.:
ChEMBL ID:CHEMBL25993
DSSTox Substance ID:DTXSID50242574

Synonyms:BRN 5620624;Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-;96825-89-7;6-(1-Azetidinyl)-3-(p-methoxyphenyl)pyridazino(4,3-c)isoquinoline;CHEMBL25993;SCHEMBL10742114;DTXSID50242574

Suppliers and Price of Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:342.14806121
Heavy Atom Count:26
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NN=C3C4=CC=CC=C4C(=NC3=C2)N5CCC5

Technology Process of Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)-

There total 5 articles about Pyridazino(4,3-c)isoquinoline, 6-(1-azetidinyl)-3-(p-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 503-29-7
azetidine

: 96825-79-5
6-Chloro-3-(4-methoxy-phenyl)-pyridazino[4,3-c]isoquinoline

: 96825-89-7
6-(1-Azetidinyl)-3-(4-methoxyphenyl)pyridazino[4,3-c]isoquinoline

Guidance literature:: In diethylene glycol dimethyl ether; at 120 - 140 ℃; for 8h;
DOI:10.1021/jm00147a034

Reference yield:

: 96825-75-1
3-(4-Methoxy-phenyl)-5H-pyridazino[4,3-c]isoquinolin-6-one

: 96825-89-7
6-(1-Azetidinyl)-3-(4-methoxyphenyl)pyridazino[4,3-c]isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / phosphorus pentachloride, phosphorus oxychloride, pyridine / 4.5 h / Heating

2: 93 percent / bis-(2-methoxy-ethyl) ether / 8 h / 120 - 140 °C

With pyridine; phosphorus pentachloride; trichlorophosphate; In diethylene glycol dimethyl ether;
DOI:10.1021/jm00147a034

Reference yield:

: 96825-72-8
2-(4-Methoxy-phenyl)-10-oxa-3,4-diaza-phenanthren-9-one

: 96825-89-7
6-(1-Azetidinyl)-3-(4-methoxyphenyl)pyridazino[4,3-c]isoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium acetate / 9 h / 190 - 200 °C

2: 98 percent / phosphorus pentachloride, phosphorus oxychloride, pyridine / 4.5 h / Heating

3: 93 percent / bis-(2-methoxy-ethyl) ether / 8 h / 120 - 140 °C

With pyridine; ammonium acetate; phosphorus pentachloride; trichlorophosphate; In diethylene glycol dimethyl ether;
DOI:10.1021/jm00147a034