3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one

Base Information

Chemical Name:3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one
CAS No.:3532-76-1
Molecular Formula:C₁₈H₁₉NO₃
Molecular Weight:297.354
Hs Code.:
NSC Number:67324
DSSTox Substance ID:DTXSID60290203

Synonyms:3532-76-1;3-hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one;3-hydroxy-2-(3-methoxypropyl)-3-phenylisoindolin-1-one;NSC67324;DTXSID60290203;NSC-67324

Suppliers and Price of 3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one

Chemical Property:

Vapor Pressure:1.24E-10mmHg at 25°C
Boiling Point:495.4°C at 760 mmHg
Flash Point:253.4°C
Density:1.225g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:297.13649347
Heavy Atom Count:22
Complexity:394

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCCCN1C(=O)C2=CC=CC=C2C1(C3=CC=CC=C3)O

Technology Process of 3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one

There total 3 articles about 3-Hydroxy-2-(3-methoxypropyl)-3-phenyl-2,3-dihydro-1h-isoindol-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₀N₂O₂

: 3532-76-1
3-hydroxy-2-(3-methoxypropyl)-3-phenylisoindolin-1-one

Guidance literature:: With caesium carbonate; L-proline; copper(l) chloride; In dimethyl sulfoxide; at 60 ℃; for 9h;
DOI:10.1039/c9ob02329a

Reference yield:

: 349110-21-0
C₁₁H₁₄INO₂

: 140-29-4
phenylacetonitrile

: 3532-76-1
3-hydroxy-2-(3-methoxypropyl)-3-phenylisoindolin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) chloride; L-proline; caesium carbonate / dimethyl sulfoxide / 60 °C / Inert atmosphere

2: copper(l) chloride; L-proline; caesium carbonate / dimethyl sulfoxide / 9 h / 60 °C

With caesium carbonate; L-proline; copper(l) chloride; In dimethyl sulfoxide;
DOI:10.1039/c9ob02329a