Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester

Base Information

• Chemical Name: Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester
• CAS No.: 33454-09-0
• Molecular Formula: C14H12O4
• Molecular Weight: 244.247
• DSSTox Substance ID: DTXSID50465847
• Nikkaji Number: J956.219B
• Wikidata: Q82292109

Synonyms:phenyl 4-methoxysalicylate;33454-09-0;phenyl 2-hydroxy-4-methoxybenzoate;Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester;SCHEMBL1484204;DTXSID50465847;BUWCUEWPPXQCIA-UHFFFAOYSA-N

Chemical Property of Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 244.07355886
• Heavy Atom Count: 18
• Complexity: 273

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)C(=O)OC2=CC=CC=C2)O

Technology Process of Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester

There total 3 articles about Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-methoxy-2-phenoxy-benzoic acid (861525-80-6) → phenyl 2-hydroxy-4-methoxybenzoate (33454-09-0)

Guidance literature:

With dipotassium hydrogenphosphate; 9-(2-mesityl)-10-methylacridinium perchlorate; In acetonitrile; at 40 ℃; for 26h; Reagent/catalyst; Irradiation; Inert atmosphere;

DOI:10.1002/anie.201706597

Reference yield:

4-hydroxysalicylic acid (89-86-1) → phenyl 2-hydroxy-4-methoxybenzoate (33454-09-0)

Guidance literature:

Multi-step reaction with 2 steps

2: POCl₃

With trichlorophosphate;

DOI:10.1021/ja00742a024

Reference yield:

→ phenyl 2-hydroxy-4-methoxybenzoate (33454-09-0)

Guidance literature:

Diketon 2b, Phenol, Bestrahlung;

DOI:10.1016/0040-4020(79)88017-5

upstream raw materials:

4-hydroxysalicylic acid

4-methoxy-2-phenoxy-benzoic acid

Downstream raw materials:

phenyl-N-butylcarbamate

2-hydroxy-4-methoxy-N-(6-methyl-pyridin-2-yl)-benzamide

2-hydroxy-4-methoxy-N-(4-methyl-pyridin-2-yl)-benzamide

2-hydroxy-N-(3-hydroxy-pyridin-2-yl)-4-methoxy-benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 33454-09-0 Benzoic acid, 2-hydroxy-4-methoxy-, phenyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send