Seproxetine

Base Information

Chemical Name:Seproxetine
CAS No.:126924-38-7
Molecular Formula:C16H16 F3 N O
Molecular Weight:295.304
Hs Code.:2922299090
UNII:25CO3X0R31
DSSTox Substance ID:DTXSID001019529,DTXSID50891581
Nikkaji Number:J511.686D
Wikipedia:Seproxetine
Wikidata:Q63395592
NCI Thesaurus Code:C75177
Pharos Ligand ID:9V2X6ZD2JJ8N
Metabolomics Workbench ID:149938
ChEMBL ID:CHEMBL465123
Mol file:126924-38-7.mol

Synonyms:(S)-Norfluoxetine;SEPROXETINE;126924-38-7;(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;Seproxetine [INN];(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE;UNII-25CO3X0R31;Norfluoxetine, (s)-;(S)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine;CHEMBL465123;25CO3X0R31;S-Norfluoxetine;Benzenepropanamine, .gamma.-[4-(trifluoromethyl)phenoxy]-, (.gamma.S)-;BENZENEPROPANAMINE, .GAMMA.-(4-(TRIFLUOROMETHYL)PHENOXY)-, (.GAMMA.S)-;D08AWN;SEPROXETINE [WHO-DD];SCHEMBL272873;(S)-3-(4-Trifluoromethylphenoxy)-3-phenylpropylamine;DTXSID50891581;WIQRCHMSJFFONW-HNNXBMFYSA-N;DTXSID001019529;BDBM50254790;AKOS027384574;DB06731;NFL_296.1257_14.5;J-005451;Q63395592

Suppliers and Price of Seproxetine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-Norfluoxetine
2.5mg
$ 185.00

SynQuest Laboratories
1-[(1S)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene 96%
250 mg
$ 1193.00

SynQuest Laboratories
1-[(1S)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene 96%
1 g
$ 3195.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
5g
$ 6900.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
1g
$ 1880.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
100mg
$ 325.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
50mg
$ 212.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
500mg
$ 998.00

J&W Pharmlab
(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine 96%
250mg
$ 549.00

American Custom Chemicals Corporation
(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE 95.00%
5MG
$ 505.78

Total 8 raw suppliers

Chemical Property of Seproxetine

Chemical Property:

Vapor Pressure:5.21E-06mmHg at 25°C
Refractive Index:1.525
Boiling Point:381.1°C at 760 mmHg
Flash Point:184.3°C
PSA：35.25000
Density:1.204g/cm³
LogP:4.87460
Storage Temp.:Hygroscopic, -20?C Freezer, Under Inert Atmosphere
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:295.11839862
Heavy Atom Count:21
Complexity:294

Purity/Quality:

97% ^*data from raw suppliers

(S)-Norfluoxetine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F
Isomeric SMILES:C1=CC=C(C=C1)[C@H](CCN)OC2=CC=C(C=C2)C(F)(F)F
Uses A metabolite of Fluoxetine (F597100), a selective serotonin reuptake inhibitor which is used as an antidepressant. (S)-Norfluoxetine is a labelled Fluoxetine (F597100) derivative,it is a stereoselective inhibitorof serotonin re-uptake and phosphodiesterase. It is used as a potential antidepressants. A labelled metabolite of Fluoxetine, a selective serotonin reuptake inhibitor which is used as an antidepressant. A metabolite of Fluoxetine, a selective serotonin reuptake inhibitor which is used as an antidepressant.

Technology Process of Seproxetine

There total 16 articles about Seproxetine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%