Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester

Base Information

Chemical Name:Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester
CAS No.:334927-88-7
Molecular Formula:C12H14O5
Molecular Weight:238.24
Hs Code.:
DSSTox Substance ID:DTXSID50470734
Nikkaji Number:J2.347.912E

Synonyms:334927-88-7;Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester;DTXSID50470734

Suppliers and Price of Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:238.08412354
Heavy Atom Count:17
Complexity:283

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC(C1=CC=CC=C1)(C(=O)OC)O

Technology Process of Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester

There total 1 articles about Butanedioic acid, 2-hydroxy-2-phenyl-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4358-87-6
(RS)-methyl mandelate

: 334927-88-7
2-hydroxy-2-phenylsuccinic acid dimethyl ester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1016/S0040-4020(00)01097-8

Reference yield: 92.0%

: 334927-88-7
2-hydroxy-2-phenylsuccinic acid dimethyl ester

: 29576-99-6
dimethyl 2-(phenyl)maleate

Guidance literature:: With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jo060586t

Reference yield:

: 334927-88-7
2-hydroxy-2-phenylsuccinic acid dimethyl ester

: 614-20-0
3-oxo-3-phenylpropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / ethanol / 20 °C

2: 50 percent / (NMe₄)Co(III)Me₂opba*2H₂O*CH₃CN; pivalaldehyde; O₂ / acetonitrile / 9.5 h / -45 °C

With potassium hydroxide; (NMe₄)Co(III)Me₂opba*2H₂O*CH₃CN; oxygen; pivalaldehyde; In ethanol; acetonitrile;
DOI:10.1016/S0040-4020(00)01097-8