3-Butenoyl chloride, 3-methyl-

Base Information

• Chemical Name: 3-Butenoyl chloride, 3-methyl-
• CAS No.: 3350-77-4
• Molecular Formula: C5H7ClO
• Molecular Weight: 118.563
• Hs Code.: 2916190090
• Mol file: 3350-77-4.mol

Synonyms:3-methyl-3-butenoyl chloride;3-Methyl-but-3-enoyl chloride;3-Butenoyl chloride,3-methyl;

Chemical Property of 3-Butenoyl chloride, 3-methyl-

Chemical Property:

• PSA: 17.07000
• LogP: 1.71800

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Butenoyl chloride, 3-methyl-

There total 4 articles about 3-Butenoyl chloride, 3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-methylbut-3-enoic acid (1617-31-8) → 3-methylbut-3-enoyl chloride (3350-77-4)

Guidance literature:

With thionyl chloride; Ambient temperature;

DOI:10.1246/bcsj.55.3555

Reference yield:

2-methyl-1-buten-4-ol (763-32-6) → 3-methylbut-3-enoyl chloride (3350-77-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / Jones reagent / acetone / 1 h / 0 °C

2: SOCl₂ / 4 h

With thionyl chloride; jones reagent; In acetone;

DOI:10.1021/ja00398a021

Reference yield:

3-methyl-3-butene nitrile (4786-19-0) → 3-methylbut-3-enoyl chloride (3350-77-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / aq. NaOH, H₂O₂, tetra-n-butylammonium iodide / CH₂Cl₂ / 144 h / 20 °C

2: oxalyl chloride / CH₂Cl₂ / 1.) 0 deg C, 30 min, 2.) 20 deg C, overnight

With sodium hydroxide; oxalyl dichloride; dihydrogen peroxide; tetra-(n-butyl)ammonium iodide; In dichloromethane;

DOI:10.1016/S0040-4020(98)00519-5

upstream raw materials:

3-methylbut-3-enoic acid

3-methyl-3-butene nitrile

2-methyl-1-buten-4-ol

Downstream raw materials:

2,5-Dimethyl-7,7-diphenyl-6,7-dihydro-pyrazolo[1,5-a]pyridine

3-Methyl-but-3-enoic acid (2-iodo-phenyl)-methyl-amide

3-Methyl-2-cyclopenten-1-one

cis-1-(p-anisyl)-4-(formyl)-3-isopropylidene-2-azetidinone

Refernces

• 1、 Singh, Parvesh,Marwaha, Alka,Singh, Harmeet,Mahajan, Mohinder P.. "Comparative reactivity of N′-(5-benzoyl/ethoxycarbonyl)thiazol-2-yl- N,N-dimethylformamidines with ketenes". . p. 11999 - 12005. Retrieved 2007/10/03.
• 2、 Fujisawa, Tamotsu,Sato, Toshio,Gotoh, Yoshihiko,Kawashima, Masatoshi,Kawara, Tatsuo. "Reaction of Diketene with Grignard Reagents in the Presence of Cobalt Catalyst. A Convenient Method for the Synthesis of 3-Methylenealkanoic Acids Leading to Terpenoids". . p. 3555 - 3559. Retrieved 2007/10/02.