Ribothymidine 3'-monophosphate

Base Information

• Chemical Name: Ribothymidine 3'-monophosphate
• CAS No.: 3352-22-5
• Molecular Formula: C10H15N2O9P
• UNII: 796M1I7H8N
• Mol file: 3352-22-5.mol

Synonyms:Ribothymidine 3'-monophosphate;3'-Uridylic acid, 5-methyl-;5-Methy-3'-uridinemonophosphate;796M1I7H8N;UNII-796M1I7H8N;Uridine, 5-methyl-, 3'-(dihydrogen phosphate);3352-22-5;SCHEMBL1904388

Chemical Property of Ribothymidine 3'-monophosphate

Chemical Property:

• XLogP3: -3.6
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 338.05151706
• Heavy Atom Count: 22
• Complexity: 559

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)OP(=O)(O)O)O
• Isomeric SMILES: CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)OP(=O)(O)O)O

Technology Process of Ribothymidine 3'-monophosphate

There total 1 articles about Ribothymidine 3'-monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H13Cl2N2O7P → O2',O3'-hydroxyphosphoryl-5-methyl-uridine (47139-37-7) + thymidine-3'-phosphate (3352-22-5) + uridine 5'-(tetrahydrogen triphosphate) (23198-01-8,66097-68-5,80160-12-9) + Phosphoric acid mono-[(2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester

Guidance literature:

C₁₀H₁₃Cl₂N₂O₇P; With trimethyl phosphite; tri-n-butylammonium phosphate; tributyl-amine; In N,N-dimethyl-formamide; at 0 - 4 ℃;

With trimethyl phosphite; triethylamine carbonate; In water; N,N-dimethyl-formamide; at 0 - 20 ℃; Further byproducts given;

DOI:10.1016/S0223-5234(99)00211-1

Reference yield:

C7H8NO2 (36455-39-7) + thymidine-3'-phosphate (3352-22-5) → 1-methyl-4-carboxypyridinium chloride (5746-18-9) + C10H15N2O9P(1-)

Guidance literature:

In water; at 20 ℃; Rate constant; Equilibrium constant; pH 8.7;

Downstream raw materials:

1-methyl-4-carboxypyridinium chloride