4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester

Base Information

• Chemical Name: 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester
• CAS No.: 117326-13-3
• Molecular Formula: C₃₉H₄₉NO₁₇
• Molecular Weight: 803.815
• Mol file: 117326-13-3.mol

Synonyms:

Chemical Property of 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester

There total 1 articles about 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

levulinic anhydride (40608-06-8) + acetic anhydride (108-24-7) + Benzoic acid (2R,3S,4R,5R,6S)-4-acetoxy-5-benzyloxycarbonylamino-3-((2S,3R,4S,5R,6S)-3,5-diacetoxy-6-acetoxymethyl-4-benzyloxy-tetrahydro-pyran-2-yloxy)-6-methoxy-tetrahydro-pyran-2-ylmethyl ester (117326-12-2) → 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester (117326-13-3)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(00)80214-2

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 4-Oxo-pentanoic acid (2S,3R,4S,5R,6S)-5-acetoxy-6-((2R,3S,4R,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxycarbonylamino-6-methoxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl ester (117326-13-3) → methyl (methyl 2-O-acetyl-3-O-benzyl-α-L-idopyrnosiduronate)-(1->4)-3,6-di-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside (117349-11-8)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(00)80214-2

upstream raw materials:

levulinic anhydride

acetic anhydride

Benzoic acid (2R,3S,4R,5R,6S)-4-acetoxy-5-benzyloxycarbonylamino-3-((2S,3R,4S,5R,6S)-3,5-diacetoxy-6-acetoxymethyl-4-benzyloxy-tetrahydro-pyran-2-yloxy)-6-methoxy-tetrahydro-pyran-2-ylmethyl ester

Downstream raw materials:

methyl (methyl 2-O-acetyl-3-O-benzyl-α-L-idopyrnosiduronate)-(1->4)-3,6-di-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside