2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid

Base Information

Chemical Name:2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid
CAS No.:75381-40-7
Molecular Formula:C₁₅H₁₄O₃
Molecular Weight:242.274
Hs Code.:
NSC Number:159330
DSSTox Substance ID:DTXSID00303609

Synonyms:75381-40-7;2-methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid;NSC159330;SCHEMBL11154852;DTXSID00303609;AKOS010910472;NSC-159330

Suppliers and Price of 2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid

Chemical Property:

Vapor Pressure:3.36E-09mmHg at 25°C
Boiling Point:458.5°C at 760 mmHg
Flash Point:245.2°C
Density:1.213g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:242.094294304
Heavy Atom Count:18
Complexity:324

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC(=O)C1=CC=CC2=CC=CC=C21)C(=O)O

Technology Process of 2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid

There total 5 articles about 2-Methyl-4-(naphthalen-1-yl)-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 97277-96-8
2-methyl-2-(1-naphtoylmethyl)malonic acid

: 75381-40-7
2-methyl-3-(1-napthoyl)propanoic acid

Guidance literature:: at 192 - 210 ℃;
DOI:10.1021/jo00218a027

Reference yield:

: 2-Methyl-2-(2-naphthalen-1-yl-2-oxo-ethyl)-malonic acid diethyl ester

: 75381-40-7
2-methyl-3-(1-napthoyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH, water / methanol / 45 h / Heating

2: 97 percent / 192 - 210 °C

With sodium hydroxide; water; In methanol;
DOI:10.1021/jo00218a027

Reference yield:

: 13686-51-6
2-bromoaceto-1-naphthone

: 75381-40-7
2-methyl-3-(1-napthoyl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) 0 deg C, 2.) glyme, RT, overnight

2: NaOH, water / methanol / 45 h / Heating

3: 97 percent / 192 - 210 °C

With sodium hydroxide; water; sodium hydride; In methanol;
DOI:10.1021/jo00218a027