2-[2-(4-Bromophenyl)-2-oxoethoxy]benzamide

Base Information

• Chemical Name: 2-[2-(4-Bromophenyl)-2-oxoethoxy]benzamide
• CAS No.: 337925-74-3
• Molecular Formula: C15H12BrNO3
• Molecular Weight: 334.16500
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID00354111
• Wikidata: Q82132073
• Mol file: 337925-74-3.mol

Synonyms:2-[2-(4-bromophenyl)-2-oxoethoxy]benzamide;337925-74-3;2-(2-(4-Bromophenyl)-2-oxoethoxy)benzamide;AKOS BC-1738;Cambridge id 6034708;Oprea1_582576;Oprea1_683808;SCHEMBL6203140;DTXSID00354111;STL444058;AKOS004120687

Chemical Property of 2-[2-(4-Bromophenyl)-2-oxoethoxy]benzamide

Chemical Property:

• Vapor Pressure: 1.86E-11mmHg at 25°C
• Boiling Point: 533.4oC at 760 mmHg
• Flash Point: 276.4oC
• PSA: 69.39000
• Density: 1.49g/cm3
• LogP: 3.51000
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 333.00006
• Heavy Atom Count: 20
• Complexity: 353

Purity/Quality:

99% ^*data from raw suppliers

2-[2-(4-BROMOPHENYL)-2-OXOETHOXY]BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)N)OCC(=O)C2=CC=C(C=C2)Br

Technology Process of 2-[2-(4-Bromophenyl)-2-oxoethoxy]benzamide

There total 2 articles about 2-[2-(4-Bromophenyl)-2-oxoethoxy]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

para-bromophenacyl bromide (99-73-0,132309-76-3) + salicylamide (65-45-2) → 2-(2-(4-bromophenyl)-2-oxoethoxy)benzamide (337925-74-3)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 7h; Reflux;

Reference yield:

→ 2-(2-(4-bromophenyl)-2-oxoethoxy)benzamide (337925-74-3)

Guidance literature:

Reference yield: 95.0%

2-(2-(4-bromophenyl)-2-oxoethoxy)benzamide (337925-74-3) → 3-(4-bromophenyl)-1,4-benzoxazepin-5(4H)-one

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 70 ℃;

upstream raw materials:

para-bromophenacyl bromide

salicylamide