7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine

Base Information

Chemical Name:7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS No.:338793-17-2
Molecular Formula:C9H7N5S
Molecular Weight:217.254
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30377318
Wikidata:Q82166493
Mol file:338793-17-2.mol

Synonyms:338793-17-2;7-(2-thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine;7-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine;7-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine;SCHEMBL3159684;DTXSID30377318;OOOMCZWDEQGXMD-UHFFFAOYSA-N;MFCD00232507;AKOS005070685;6H-035;J-519045;7-thiophen-2-yl[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Suppliers and Price of 7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine >95%
5g
$ 698.00

Matrix Scientific
7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine >95%
1g
$ 304.00

Matrix Scientific
7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine >95%
500mg
$ 244.00

Crysdot
7-(Thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine 95+%
5g
$ 432.00

Arctom
7-(Thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine ≥95%
1g
$ 145.00

AK Scientific
7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
5g
$ 992.00

AK Scientific
7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
1g
$ 460.00

Total 5 raw suppliers

Chemical Property of 7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine

Chemical Property:

Melting Point:252-254°C
PKA:3.10±0.30(Predicted)
PSA：98.07000
Density:1.69±0.1 g/cm3(Predicted)
LogP:1.36510
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:217.04221642
Heavy Atom Count:15
Complexity:239

Purity/Quality:

98%min ^*data from raw suppliers

7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CSC(=C1)C2=CC=NC3=NC(=NN23)N

Technology Process of 7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine

There total 2 articles about 7-(2-Thienyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1455-77-2
guanazole

: 34772-98-0,154321-55-8,265103-28-4
3-dimethylamino-1-thiophen-2-ylpropenone

: 338793-17-2
7-thiophen-2-yl[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Guidance literature:: With (1S)-10-camphorsulfonic acid; In toluene; at 100 ℃; for 1.5h; Heating / reflux;

Reference yield:

: 1455-77-2
guanazole

: 34772-98-0,154321-55-8,265103-28-4
3-dimethylamino-1-thiophen-2-ylpropenone

: 338793-17-2
7-thiophen-2-yl[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Guidance literature:: guanazole; 3-dimethylamino-1-thiophen-2-ylpropenone; In toluene; at 100 ℃;

With camphor-10-sulfonic acid; In toluene; for 1.5h; Heating / reflux;

Reference yield: 63.0%

: 338793-17-2
7-thiophen-2-yl[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

: 6,6-dimethyl-4-oxo-5,6-dihydro-4H-pyran-2-carboxylic acid N-(7-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)amide

Guidance literature:: 3,4-dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylic acid; With oxalyl dichloride; In tetrahydrofuran; at 20 ℃; for 1h;

7-thiophen-2-yl[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine; With pyridine; dmap; In tetrahydrofuran; at 20 ℃;