1-butyl-4-fluoro-benzene

Base Information

• Chemical Name: 1-butyl-4-fluoro-benzene
• CAS No.: 20651-65-4
• Molecular Formula: C10H13F
• Molecular Weight: 152.212
• Hs Code.: 2903999090
• Mol file: 20651-65-4.mol

Synonyms:p-fluorophenyl-butane;1-BUTYL-4-FLUORO-BENZENE;4-butylfluorobenzene;Benzene,1-butyl-4-fluoro;p-Fluorbutylbenzol;4-n-butyl-fluorobenzene;p-Fluor-n-butylbenzol;

Chemical Property of 1-butyl-4-fluoro-benzene

Chemical Property:

• Vapor Pressure: 0.863mmHg at 25°C
• Boiling Point: 188℃
• Flash Point: 59℃
• PSA: 0.00000
• Density: 0.954
• LogP: 3.16830

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-butyl-4-fluoro-benzene

There total 32 articles about 1-butyl-4-fluoro-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-Butylaniline (104-13-2) → 4-(n-butyl)fluorobenzene (20651-65-4)

Guidance literature:

4-Butylaniline; With tetrafluoroboric acid; sodium nitrite;

In cyclohexane; Heating;

DOI:10.1021/ja509144r

Reference yield: 91.0%

p-bromobutylbenzene (41492-05-1) → 3-(n-butyl)fluorobenzene (20651-66-5) + 4-(n-butyl)fluorobenzene (20651-65-4)

Guidance literature:

With potassium fluoride; C₅₉H₇₁BrF₇OPPd; silver fluoride; cyclo-octa-1,5-diene; In cyclohexane; at 90 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.7b01082

Reference yield: 90.0%

n-butyllithium (109-72-8,29786-93-4) + 1-Bromo-4-fluorobenzene (460-00-4) → 4-(n-butyl)fluorobenzene (20651-65-4)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; water; sodium chloride; In cyclohexane; at 20 ℃; for 0.00555556h; pH=6; Schlenk technique;

DOI:10.1002/anie.201812537

upstream raw materials:

1-(4-Butylphenyl)-3,3-(1,5-pentanediyl)triazene

C₁₂H₁₃FO₄

C₁₃H₁₅FO₄

C₁₈H₁₆ClFO₄

Downstream raw materials:

Clopimozide