4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Base Information

• Chemical Name: 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester
• CAS No.: 244611-82-3
• Molecular Formula: C₂₇H₃₇N₂O₁₀P
• Molecular Weight: 580.572

Synonyms:

Chemical Property of 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

There total 4 articles about 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

4-Methyl-benzoic acid (2R,3S,4R,5S)-3,5-diacetoxy-4-(diisopropoxy-phosphorylmethyl)-tetrahydro-furan-2-ylmethyl ester → 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (244611-82-3)

Guidance literature:

DOI:10.1080/07328319908044681

Reference yield:

4-Methyl-benzoic acid (2R,3S,4R)-3,5-diacetoxy-4-methanesulfonyloxymethyl-tetrahydro-furan-2-ylmethyl ester → 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (244611-82-3)

Guidance literature:

Multi-step reaction with 3 steps

2: NaI; Bu₄I

With sodium iodide; 1: Substitution / 2: Substitution / 3: Substitution;

DOI:10.1080/07328319908044681

Reference yield:

4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-methanesulfonyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester → 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (244611-82-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaI; Bu₄I

With sodium iodide; 1: Substitution / 2: Substitution;

DOI:10.1080/07328319908044681

upstream raw materials:

triisopropyl phosphite

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 244611-82-3 4-Methyl-benzoic acid (2R,3S,4R,5R)-3-acetoxy-4-(diisopropoxy-phosphorylmethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send